Phase 3 — Large-scale testing across thousands of people, comparing the new treatment against current standard treatments.
Trial locations(214 sites)
United States
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama Saint Joseph's Hospital and Medical Center, Phoenix, Arizona Mayo Clinic Hospital in Arizona, Phoenix, Arizona Mayo Clinic in Arizona, Scottsdale, Arizona University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona Banner University Medical Center - Tucson, Tucson, Arizona University of Arizona Cancer Center-North Campus, Tucson, Arizona Kaiser Permanente-Anaheim, Anaheim, California Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn, California Kaiser Permanente-Bellflower, Bellflower, California Kaiser Permanente Dublin, Dublin, California Kaiser Permanente Los Angeles Medical Center, Los Angeles, California Los Angeles General Medical Center, Los Angeles, California USC / Norris Comprehensive Cancer Center, Los Angeles, California Memorial Medical Center, Modesto, California Kaiser Permanente Oakland-Broadway, Oakland, California Kaiser Permanente-Ontario, Ontario, California UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California Stanford Cancer Institute Palo Alto, Palo Alto, California Kaiser Permanente-Rancho Cordova Cancer Center, Rancho Cordova, California Rohnert Park Cancer Center, Rohnert Park, California Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California The Permanente Medical Group-Roseville Radiation Oncology, Roseville, California Sutter Medical Center Sacramento, Sacramento, California South Sacramento Cancer Center, Sacramento, California California Pacific Medical Center-Pacific Campus, San Francisco, California Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California Kaiser Permanente Cancer Treatment Center, South San Francisco, California Sutter Solano Medical Center/Cancer Center, Vallejo, California Hartford Hospital, Hartford, Connecticut Yale University, New Haven, Connecticut Smilow Cancer Hospital Care Center-Trumbull, Trumbull, Connecticut Helen F Graham Cancer Center, Newark, Delaware Christiana Care Health System-Christiana Hospital, Newark, Delaware Beebe Health Campus, Rehoboth Beach, Delaware TidalHealth Nanticoke / Allen Cancer Center, Seaford, Delaware Boca Raton Regional Hospital, Boca Raton, Florida UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida UM Sylvester Comprehensive Cancer Center at Doral, Doral, Florida Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida Baptist MD Anderson Cancer Center, Jacksonville, Florida University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida Miami Cancer Institute, Miami, Florida AdventHealth Orlando, Orlando, Florida AdventHealth East Orlando, Orlando, Florida Memorial Hospital West, Pembroke Pines, Florida UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida Moffitt Cancer Center, Tampa, Florida Grady Health System, Atlanta, Georgia Emory Proton Therapy Center, Atlanta, Georgia Piedmont Hospital, Atlanta, Georgia Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia Emory Saint Joseph's Hospital, Atlanta, Georgia Northside Hospital, Atlanta, Georgia Northside Hospital-Forsyth, Cumming, Georgia Piedmont Fayette Hospital, Fayetteville, Georgia Piedmont Newnan Hospital, Newnan, Georgia Piedmont Henry Hospital, Stockbridge, Georgia Queen's Medical Center, Honolulu, Hawaii The Cancer Center of Hawaii-Liliha, Honolulu, Hawaii Northwestern University, Chicago, Illinois Rush MD Anderson Cancer Center, Chicago, Illinois University of Illinois, Chicago, Illinois Decatur Memorial Hospital, Decatur, Illinois NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois Northwestern Medicine Cancer Center Delnor, Geneva, Illinois NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois Loyola University Medical Center, Maywood, Illinois Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana IU Health Methodist Hospital, Indianapolis, Indiana Iowa Methodist Medical Center, Des Moines, Iowa University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa University of Kansas Cancer Center, Kansas City, Kansas University of Kansas Cancer Center-Overland Park, Overland Park, Kansas University of Kentucky/Markey Cancer Center, Lexington, Kentucky The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky UofL Health Medical Center Northeast, Louisville, Kentucky LSU Health Sciences Center at Shreveport, Shreveport, Louisiana MaineHealth Coastal Cancer Treatment Center, Bath, Maine MaineHealth Maine Medical Center - Portland, Portland, Maine MaineHealth Cancer Care Center of York County, Sanford, Maine MaineHealth Maine Medical Center- Scarborough, Scarborough, Maine Maryland Proton Treatment Center, Baltimore, Maryland University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland Tufts Medical Center, Boston, Massachusetts Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan University of Michigan Rogel Cancer Center, Ann Arbor, Michigan Chelsea Hospital, Chelsea, Michigan Henry Ford Macomb Hospital-Clinton Township, Clinton Township, Michigan Henry Ford Hospital, Detroit, Michigan Henry Ford Health Saint John Hospital, Detroit, Michigan Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan MyMichigan Medical Center Saginaw, Saginaw, Michigan Henry Ford Health Warren Hospital, Warren, Michigan Henry Ford West Bloomfield Hospital, West Bloomfield, Michigan University of Michigan Health - West, Wyoming, Michigan Essentia Health Cancer Center, Duluth, Minnesota Miller-Dwan Hospital, Duluth, Minnesota Abbott-Northwestern Hospital, Minneapolis, Minnesota Mayo Clinic in Rochester, Rochester, Minnesota Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota Regions Hospital, Saint Paul, Minnesota University of Mississippi Medical Center, Jackson, Mississippi Siteman Cancer Center at Saint Peters Hospital, City of Saint Peters, Missouri MU Health - University Hospital/Ellis Fischel Cancer Center, Columbia, Missouri Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri Washington University School of Medicine, St Louis, Missouri Siteman Cancer Center-South County, St Louis, Missouri Billings Clinic Cancer Center, Billings, Montana Benefis Sletten Cancer Institute, Great Falls, Montana Logan Health Medical Center, Kalispell, Montana University of Nebraska Medical Center, Omaha, Nebraska Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey Memorial Sloan Kettering Monmouth, Middletown, New Jersey Memorial Sloan Kettering Bergen, Montvale, New Jersey Jersey Shore Medical Center, Neptune City, New Jersey Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey Rutgers New Jersey Medical School, Newark, New Jersey Capital Health Medical Center-Hopewell, Pennington, New Jersey ProCure Proton Therapy Center-Somerset, Somerset, New Jersey Robert Wood Johnson University Hospital Somerset, Somerville, New Jersey University of New Mexico Cancer Center, Albuquerque, New Mexico New York-Presbyterian/Brooklyn Methodist Hospital, Brooklyn, New York Memorial Sloan Kettering Commack, Commack, New York The New York Hospital Medical Center of Queens, Flushing, New York Memorial Sloan Kettering Westchester, Harrison, New York NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York Memorial Sloan Kettering Cancer Center, New York, New York NYP/Weill Cornell Medical Center, New York, New York University of Rochester, Rochester, New York Memorial Sloan Kettering Nassau, Uniondale, New York Westchester Medical Center, Valhalla, New York UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina Case Western Reserve University, Cleveland, Ohio Cleveland Clinic Foundation, Cleveland, Ohio Ohio State University Comprehensive Cancer Center, Columbus, Ohio Mercy Cancer Center-Elyria, Elyria, Ohio Kettering Medical Center, Kettering, Ohio UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor, Ohio ProMedica Flower Hospital, Sylvania, Ohio UHHS-Westlake Medical Center, Westlake, Ohio University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma Legacy Mount Hood Medical Center, Gresham, Oregon Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon Saint Luke's University Hospital-Bethlehem Campus, Bethlehem, Pennsylvania Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania Geisinger Medical Center, Danville, Pennsylvania Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania Lewistown Hospital, Lewistown, Pennsylvania Thomas Jefferson University Hospital, Philadelphia, Pennsylvania Fox Chase Cancer Center, Philadelphia, Pennsylvania Temple University Hospital, Philadelphia, Pennsylvania Geisinger Cancer Services-Pottsville, Pottsville, Pennsylvania Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania Lankenau Medical Center, Wynnewood, Pennsylvania Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina Medical University of South Carolina, Charleston, South Carolina Prisma Health Cancer Institute - Faris, Greenville, South Carolina Prisma Health Cancer Institute - Eastside, Greenville, South Carolina Prisma Health Cancer Institute - Greer, Greer, South Carolina Prisma Health Cancer Institute - Seneca, Seneca, South Carolina Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas M D Anderson Cancer Center, Houston, Texas University of Texas Health Science Center at San Antonio, San Antonio, Texas American Fork Hospital / Huntsman Intermountain Cancer Center, American Fork, Utah Logan Regional Hospital, Logan, Utah Intermountain Medical Center, Murray, Utah McKay-Dee Hospital Center, Ogden, Utah Utah Valley Regional Medical Center, Provo, Utah Riverton Hospital, Riverton, Utah LDS Hospital, Salt Lake City, Utah Dartmouth Cancer Center - North, Saint Johnsbury, Vermont VCU Massey Comprehensive Cancer Center, Richmond, Virginia University of Washington Medical Center - Montlake, Seattle, Washington Legacy Salmon Creek Hospital, Vancouver, Washington Langlade Hospital and Cancer Center, Antigo, Wisconsin Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin Marshfield Medical Center-Marshfield, Marshfield, Wisconsin Froedtert Menomonee Falls Hospital, Menomonee Falls, Wisconsin Medical College of Wisconsin, Milwaukee, Wisconsin Marshfield Medical Center - Minocqua, Minocqua, Wisconsin Drexel Town Square Health Center, Oak Creek, Wisconsin Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin Aspirus Cancer Care - Stevens Point, Stevens Point, Wisconsin Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin UW Cancer Center at ProHealth Care, Waukesha, Wisconsin Aspirus Regional Cancer Center, Wausau, Wisconsin Marshfield Medical Center - Weston, Weston, Wisconsin Aspirus Cancer Care - Wisconsin Rapids, Wisconsin Rapids, Wisconsin Canada
Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta Cross Cancer Institute, Edmonton, Alberta Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario London Regional Cancer Program, London, Ontario University Health Network-Princess Margaret Hospital, Toronto, Ontario CHUM - Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec The Research Institute of the McGill University Health Centre (MUHC), Montreal, Quebec Allan Blair Cancer Centre, Regina, Saskatchewan India
Tata Memorial Hospital, Mumbai Japan
Hokkaido University Hospital, Sapporo, Hokkaido Iwate Medical University Hospital, Shiwa-gun, Iwate Kyorin University Hospital, Mitaka-shi, Tokyo Keio University, Shinjuku-ku, Tokyo Hiroshima University Hospital, Hiroshima Saitama Medical University International Medical Center, Saitama National Cancer Center Hospital, Tokyo Saudi Arabia
King Faisal Specialist Hospital and Research Centre, Riyadh Last updated January 2026