Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.
(45 sites) United States
St. Joseph's Hospital and Medical Center, Phoenix, Arizona Mayo Clinic, Phoenix, Arizona City of Hope, Duarte, California Providence St. John's Health Center, Santa Monica, California UCLA Department of Medicine - Hematology/Oncology, Santa Monica, California Smilow Cancer Hospital at Yale-New Haven, New Haven, Connecticut Mayo Clinic, Jacksonville, Florida Northwestern Memorial Hospital, Chicago, Illinois Dana Farber Cancer Institute, Boston, Massachusetts Mayo Clinic, Rochester, Minnesota Fred and Pamela Buffett Cancer Center, Omaha, Nebraska Hackensack University Medical Center, Hackensack, New Jersey Roswell Park Comprehensive Cancer Center, Buffalo, New York Mt Sinai, New York, New York Columbia University Irving Medical Center, New York, New York Memorial Sloan Kettering Cancer Center, New York, New York Duke University Medical Center, Duke Cancer Center, Durham, North Carolina Cleveland Clinic, Cleveland, Ohio Providence Neurological Specialties West, Portland, Oregon Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania UPMC Hilman Cancer Center, Pittsburgh, Pennsylvania University of Tennessee Medical Center, Knoxville, Tennessee UT Southwestern Medical Center, Dallas, Texas The University of Texas MD Anderson Cancer Center, Houston, Texas Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah Swedish Cancer Institute, Seattle, Washington University of Washington Medical Center, Seattle, Washington Czechia
Všeobecná fakultní nemocnice v Praze, Prague France
Institut Bergonie, Bordeaux Hopital de la Timone, Marseille Hospital Pitie Salpetriere, Paris Institut Curie Hospital, Paris Israel
Hematology Department Soroka UMC / Heanatology Department, Beersheba Rambam Medical Center, Haifa Hadassah Medical Center / Ein-Carem, Jerusalem Italy
Università di Torino Croce e Carle, Cuneo SODc Ematologia Azienda Ospedaliera Universitaria Careggi, Florence IRST - Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola IRCCS San Raffaele Scientific Institute, Milan Poland
Uniwersyteckie Centrum Kliniczne Osrodek Badan Klinicznych Wczesnych Faz, Gdansk Oddzial Kliniczny Hematologii, Krakow NarodowyInstytutu Onkologii im. Marii Sklodowskiej-Curie-Panstwowy Instytutu Badawczy, Warsaw Spain
University Hospital Vall d'Hebron, Barcelona MD Anderson Cancer Center Madrid, Madrid Hospital Universitario Virgen del Rocio, Seville