Plain-English translation of NCT03917043 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new oral medication called that targets specific proteins involved in cancer growth. Researchers want to find the safest dose and learn how the medication works in patients with advanced solid tumors, particularly those with certain genetic mutations in lung cancer. This is an early-stage study designed to establish what dose works best before testing it in larger patient groups.
Laboratory studies show this medication may slow or stop cancer cell growth and work well when combined with other cancer treatments. The trial exists to determine whether this medication is safe for patients and to find the right dose to use in future studies.
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You will take the medication by mouth at home, starting at a set dose that may be increased gradually as the study progresses. You will visit the clinic regularly for blood tests, physical exams, and imaging scans to monitor how you respond and check for side effects. The study includes a dose-finding phase (where the dose is adjusted) and an expansion phase where additional patients take the established safe dose; you may participate in either phase depending on when you enroll.
AI-generated summary from trial data · Jun 27, 2026 · Not medical advice
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