Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.
(182 sites) United States
Children's Hospital of Alabama, Birmingham, Alabama USA Health Strada Patient Care Center, Mobile, Alabama Providence Alaska Medical Center, Anchorage, Alaska Banner Children's at Desert, Mesa, Arizona Phoenix Childrens Hospital, Phoenix, Arizona Banner University Medical Center - Tucson, Tucson, Arizona Arkansas Children's Hospital, Little Rock, Arkansas Kaiser Permanente Downey Medical Center, Downey, California Loma Linda University Medical Center, Loma Linda, California Miller Children's and Women's Hospital Long Beach, Long Beach, California Children's Hospital Los Angeles, Los Angeles, California Valley Children's Hospital, Madera, California UCSF Benioff Children's Hospital Oakland, Oakland, California Kaiser Permanente-Oakland, Oakland, California Children's Hospital of Orange County, Orange, California Lucile Packard Children's Hospital Stanford University, Palo Alto, California Rady Children's Hospital - San Diego, San Diego, California UCSF Medical Center-Mission Bay, San Francisco, California Children's Hospital Colorado, Aurora, Colorado Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado Connecticut Children's Medical Center, Hartford, Connecticut Yale University, New Haven, Connecticut Alfred I duPont Hospital for Children, Wilmington, Delaware MedStar Georgetown University Hospital, Washington D.C., District of Columbia Children's National Medical Center, Washington D.C., District of Columbia Broward Health Medical Center, Fort Lauderdale, Florida Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida UF Health Cancer Institute - Gainesville, Gainesville, Florida Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida Nemours Children's Clinic-Jacksonville, Jacksonville, Florida Nicklaus Children's Hospital, Miami, Florida Arnold Palmer Hospital for Children, Orlando, Florida Nemours Children's Hospital, Orlando, Florida Nemours Children's Clinic - Pensacola, Pensacola, Florida Sacred Heart Hospital, Pensacola, Florida Johns Hopkins All Children's Hospital, St. Petersburg, Florida Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida Saint Mary's Medical Center, West Palm Beach, Florida Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia Memorial Health University Medical Center, Savannah, Georgia Kapiolani Medical Center for Women and Children, Honolulu, Hawaii Saint Luke's Cancer Institute - Boise, Boise, Idaho Lurie Children's Hospital-Chicago, Chicago, Illinois University of Illinois, Chicago, Illinois University of Chicago Comprehensive Cancer Center, Chicago, Illinois Loyola University Medical Center, Maywood, Illinois Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois Saint Jude Midwest Affiliate, Peoria, Illinois Southern Illinois University School of Medicine, Springfield, Illinois Riley Hospital for Children, Indianapolis, Indiana Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana Blank Children's Hospital, Des Moines, Iowa University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa University of Kentucky/Markey Cancer Center, Lexington, Kentucky Norton Children's Hospital, Louisville, Kentucky Children's Hospital New Orleans, New Orleans, Louisiana Ochsner Medical Center Jefferson, New Orleans, Louisiana Eastern Maine Medical Center, Bangor, Maine Maine Children's Cancer Program, Scarborough, Maine Sinai Hospital of Baltimore, Baltimore, Maryland Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland Walter Reed National Military Medical Center, Bethesda, Maryland Dana-Farber Cancer Institute, Boston, Massachusetts C S Mott Children's Hospital, Ann Arbor, Michigan Children's Hospital of Michigan, Detroit, Michigan Michigan State University, East Lansing, Michigan Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan Bronson Methodist Hospital, Kalamazoo, Michigan Corewell Health Children's, Royal Oak, Michigan Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota Mayo Clinic in Rochester, Rochester, Minnesota University of Mississippi Medical Center, Jackson, Mississippi University of Missouri Children's Hospital, Columbia, Missouri Children's Mercy Hospitals and Clinics, Kansas City, Missouri Cardinal Glennon Children's Medical Center, St Louis, Missouri Washington University School of Medicine, St Louis, Missouri Mercy Hospital Saint Louis, St Louis, Missouri Children's Hospital and Medical Center of Omaha, Omaha, Nebraska University of Nebraska Medical Center, Omaha, Nebraska Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada Summerlin Hospital Medical Center, Las Vegas, Nevada Renown Regional Medical Center, Reno, Nevada Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire Hackensack University Medical Center, Hackensack, New Jersey Morristown Medical Center, Morristown, New Jersey Jersey Shore Medical Center, Neptune City, New Jersey Saint Peter's University Hospital, New Brunswick, New Jersey Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey Saint Joseph's Regional Medical Center, Paterson, New Jersey University of New Mexico Cancer Center, Albuquerque, New Mexico Albany Medical Center, Albany, New York Maimonides Medical Center, Brooklyn, New York NYU Langone Hospital - Long Island, Mineola, New York The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York Memorial Sloan Kettering Cancer Center, New York, New York University of Rochester, Rochester, New York Stony Brook University Medical Center, Stony Brook, New York State University of New York Upstate Medical University, Syracuse, New York Montefiore Medical Center - Moses Campus, The Bronx, New York New York Medical College, Valhalla, New York Mission Hospital, Asheville, North Carolina UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina Novant Health Presbyterian Medical Center, Charlotte, North Carolina Duke University Medical Center, Durham, North Carolina East Carolina University, Greenville, North Carolina Wake Forest University Health Sciences, Winston-Salem, North Carolina Sanford Broadway Medical Center, Fargo, North Dakota Children's Hospital Medical Center of Akron, Akron, Ohio Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio Rainbow Babies and Childrens Hospital, Cleveland, Ohio Cleveland Clinic Foundation, Cleveland, Ohio Nationwide Children's Hospital, Columbus, Ohio Dayton Children's Hospital, Dayton, Ohio ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma Legacy Emanuel Children's Hospital, Portland, Oregon Oregon Health and Science University, Portland, Oregon Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania Geisinger Medical Center, Danville, Pennsylvania Penn State Children's Hospital, Hershey, Pennsylvania Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania Rhode Island Hospital, Providence, Rhode Island Medical University of South Carolina, Charleston, South Carolina Prisma Health Richland Hospital, Columbia, South Carolina BI-LO Charities Children's Cancer Center, Greenville, South Carolina Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota East Tennessee Childrens Hospital, Knoxville, Tennessee Saint Jude Children's Research Hospital, Memphis, Tennessee The Children's Hospital at TriStar Centennial, Nashville, Tennessee Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee Dell Children's Medical Center of Central Texas, Austin, Texas Driscoll Children's Hospital, Corpus Christi, Texas Medical City Dallas Hospital, Dallas, Texas UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas El Paso Children's Hospital, El Paso, Texas Cook Children's Medical Center, Fort Worth, Texas Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas M D Anderson Cancer Center, Houston, Texas Covenant Children's Hospital, Lubbock, Texas UMC Cancer Center / UMC Health System, Lubbock, Texas Children's Hospital of San Antonio, San Antonio, Texas Methodist Children's Hospital of South Texas, San Antonio, Texas University of Texas Health Science Center at San Antonio, San Antonio, Texas Primary Children's Hospital, Salt Lake City, Utah University of Virginia Cancer Center, Charlottesville, Virginia Inova Fairfax Hospital, Falls Church, Virginia Children's Hospital of The King's Daughters, Norfolk, Virginia VCU Massey Comprehensive Cancer Center, Richmond, Virginia Carilion Children's, Roanoke, Virginia Seattle Children's Hospital, Seattle, Washington Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington Mary Bridge Children's Hospital and Health Center, Tacoma, Washington Madigan Army Medical Center, Tacoma, Washington West Virginia University Healthcare, Morgantown, West Virginia University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin Marshfield Medical Center-Marshfield, Marshfield, Wisconsin Australia
The Children's Hospital at Westmead, Westmead, New South Wales Queensland Children's Hospital, South Brisbane, Queensland Royal Children's Hospital, Parkville, Victoria Perth Children's Hospital, Perth, Western Australia Canada
Alberta Children's Hospital, Calgary, Alberta University of Alberta Hospital, Edmonton, Alberta British Columbia Children's Hospital, Vancouver, British Columbia CancerCare Manitoba, Winnipeg, Manitoba IWK Health Centre, Halifax, Nova Scotia Children's Hospital, London, Ontario Children's Hospital of Eastern Ontario, Ottawa, Ontario Hospital for Sick Children, Toronto, Ontario The Montreal Children's Hospital of the MUHC, Montreal, Quebec Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Québec New Zealand
Starship Children's Hospital, Grafton, Auckland Christchurch Hospital, Christchurch Puerto Rico
HIMA San Pablo Oncologic Hospital, Caguas