Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.
(42 sites) United States
University of California San Francisco - Fresno Center for Medical Education and Research, Clovis, California Scripps Health - Prebys Cancer Center, San Diego, California Sylvester Comprehensive Cancer Center, Miami, Florida Miami Cancer Institute, Miami, Florida Memorial Cancer Institute - Memorial Hospital West, Pembroke Pines, Florida Winship Cancer Institute of Emory University, Atlanta, Georgia The Blood and Marrow Transplant Group of Georgia, Atlanta, Georgia Mission Cancer + Blood - Mission Cancer Foundation, Des Moines, Iowa Beth Israel Deaconess Medical Center, Boston, Massachusetts Dana-Farber Cancer Institute, Boston, Massachusetts University of Minnesota, Minneapolis, Minnesota Columbia University Irving Medical Center, New York, New York Cleveland Clinic Main Campus, Cleveland, Ohio Oregon Health and Science University, Portland, Oregon Penn Medicine - Perelman Center for Advanced Medicine, Philadelphia, Pennsylvania Allegheny Health Network - West Penn Hospital, Pittsburgh, Pennsylvania Brown University Health - Rhode Island Hospital, Providence, Rhode Island Hollings Cancer Center, Charleston, South Carolina Avera Cancer Institute, Sioux Falls, South Dakota Greco-Hainsworth Tennessee Oncology Centers for Research (GHCR), Nashville, Tennessee Baylor University Medical Center, Dallas, Texas Huntsman Cancer Institute, Salt Lake City, Utah Emily Couric Clinical Cancer Center, Charlottesville, Virginia NEXT Virginia (Virginia Cancer Specialists), Fairfax, Virginia Froedtert & Medical College of Wisconsin, Milwaukee, Wisconsin Belgium
Universitair Ziekenhuis Gent, Ghent Centre Hospitalier Universitaire Universite Catholique de Louvain - Site Godinne, Yvoir Czechia
Fakultni Nemocnice Brno, Brno, South Moravian Fakultni nemocnice Ostrava, Ostrava Fakultní Nemocnice Královské Vinohrady, Prague Fakultni nemocnice v Motole, Prague Italy
Azienda Socio Sanitaria Territoriale (ASST) Papa Giovanni XXIII, Bergamo Centro di Ricerche Cliniche - IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna Azienda Socio Sanitaria Territoriale (ASST) degli Spedali Civili di Brescia, Brescia Istituto Europeo di Oncologia, Milan Spain
Institut Català d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet), Barcelona Hospital General Universitario Gregorio Marañón, Madrid Hospital Universitario Ramón y Cajal, Madrid Complejo Asistencial Universitario de Salamanca - Hospital Clínico, Salamanca Hospital Universitari i Politècnic La Fe, Valencia United Kingdom
University College London Hospitals NHS Foundation Trust, London Oxford University Hospitals NHS Foundation Trust, Oxford