Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.
(127 sites) United States
Children's Hospital of Alabama, Birmingham, Alabama Banner Children's at Desert, Mesa, Arizona Phoenix Childrens Hospital, Phoenix, Arizona Arkansas Children's Hospital, Little Rock, Arkansas Loma Linda University Medical Center, Loma Linda, California Miller Children's and Women's Hospital Long Beach, Long Beach, California Children's Hospital Los Angeles, Los Angeles, California Cedars Sinai Medical Center, Los Angeles, California UCSF Benioff Children's Hospital Oakland, Oakland, California Kaiser Permanente-Oakland, Oakland, California Children's Hospital of Orange County, Orange, California Lucile Packard Children's Hospital Stanford University, Palo Alto, California Rady Children's Hospital - San Diego, San Diego, California UCSF Medical Center-Mission Bay, San Francisco, California Children's Hospital Colorado, Aurora, Colorado Connecticut Children's Medical Center, Hartford, Connecticut Yale University, New Haven, Connecticut Alfred I duPont Hospital for Children, Wilmington, Delaware Children's National Medical Center, Washington D.C., District of Columbia Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida Nemours Children's Clinic-Jacksonville, Jacksonville, Florida University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida Miami Cancer Institute, Miami, Florida Arnold Palmer Hospital for Children, Orlando, Florida Nemours Children's Hospital, Orlando, Florida Johns Hopkins All Children's Hospital, St. Petersburg, Florida Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia Kapiolani Medical Center for Women and Children, Honolulu, Hawaii Saint Luke's Cancer Institute - Boise, Boise, Idaho University of Chicago Comprehensive Cancer Center, Chicago, Illinois Saint Jude Midwest Affiliate, Peoria, Illinois Riley Hospital for Children, Indianapolis, Indiana Blank Children's Hospital, Des Moines, Iowa University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa University of Kentucky/Markey Cancer Center, Lexington, Kentucky Norton Children's Hospital, Louisville, Kentucky Children's Hospital New Orleans, New Orleans, Louisiana Eastern Maine Medical Center, Bangor, Maine Maine Children's Cancer Program, Scarborough, Maine Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland Dana-Farber Cancer Institute, Boston, Massachusetts C S Mott Children's Hospital, Ann Arbor, Michigan Children's Hospital of Michigan, Detroit, Michigan Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota University of Mississippi Medical Center, Jackson, Mississippi Children's Mercy Hospitals and Clinics, Kansas City, Missouri Cardinal Glennon Children's Medical Center, St Louis, Missouri Washington University School of Medicine, St Louis, Missouri Mercy Hospital Saint Louis, St Louis, Missouri Children's Hospital and Medical Center of Omaha, Omaha, Nebraska University of Nebraska Medical Center, Omaha, Nebraska Hackensack University Medical Center, Hackensack, New Jersey Morristown Medical Center, Morristown, New Jersey Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey Newark Beth Israel Medical Center, Newark, New Jersey Saint Joseph's Regional Medical Center, Paterson, New Jersey Albany Medical Center, Albany, New York Roswell Park Cancer Institute, Buffalo, New York The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York Memorial Sloan Kettering Cancer Center, New York, New York State University of New York Upstate Medical University, Syracuse, New York Montefiore Medical Center - Moses Campus, The Bronx, New York Novant Health Presbyterian Medical Center, Charlotte, North Carolina East Carolina University, Greenville, North Carolina Wake Forest University Health Sciences, Winston-Salem, North Carolina Sanford Broadway Medical Center, Fargo, North Dakota Children's Hospital Medical Center of Akron, Akron, Ohio Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio Rainbow Babies and Childrens Hospital, Cleveland, Ohio Nationwide Children's Hospital, Columbus, Ohio Dayton Children's Hospital, Dayton, Ohio ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma Legacy Emanuel Children's Hospital, Portland, Oregon Oregon Health and Science University, Portland, Oregon Geisinger Medical Center, Danville, Pennsylvania Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania Rhode Island Hospital, Providence, Rhode Island Prisma Health Richland Hospital, Columbia, South Carolina BI-LO Charities Children's Cancer Center, Greenville, South Carolina Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota East Tennessee Childrens Hospital, Knoxville, Tennessee Saint Jude Children's Research Hospital, Memphis, Tennessee The Children's Hospital at TriStar Centennial, Nashville, Tennessee Dell Children's Medical Center of Central Texas, Austin, Texas Driscoll Children's Hospital, Corpus Christi, Texas Medical City Dallas Hospital, Dallas, Texas UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas El Paso Children's Hospital, El Paso, Texas Cook Children's Medical Center, Fort Worth, Texas Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas M D Anderson Cancer Center, Houston, Texas Children's Hospital of San Antonio, San Antonio, Texas University of Texas Health Science Center at San Antonio, San Antonio, Texas Primary Children's Hospital, Salt Lake City, Utah University of Virginia Cancer Center, Charlottesville, Virginia Children's Hospital of The King's Daughters, Norfolk, Virginia Seattle Children's Hospital, Seattle, Washington Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington Mary Bridge Children's Hospital and Health Center, Tacoma, Washington University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin Children's Hospital of Wisconsin, Milwaukee, Wisconsin Australia
Sydney Children's Hospital, Randwick, New South Wales The Children's Hospital at Westmead, Westmead, New South Wales Queensland Children's Hospital, South Brisbane, Queensland Royal Children's Hospital, Parkville, Victoria Perth Children's Hospital, Perth, Western Australia Canada
University of Alberta Hospital, Edmonton, Alberta British Columbia Children's Hospital, Vancouver, British Columbia CancerCare Manitoba, Winnipeg, Manitoba IWK Health Centre, Halifax, Nova Scotia McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario Hospital for Sick Children, Toronto, Ontario The Montreal Children's Hospital of the MUHC, Montreal, Quebec Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec Jim Pattison Children's Hospital, Saskatoon, Saskatchewan CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Québec New Zealand
Starship Children's Hospital, Grafton, Auckland Christchurch Hospital, Christchurch