Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.
(42 sites) United States
Scripps Clinic Torrey Pines, La Jolla, California Winship Cancer Institute of Emory University, Atlanta, Georgia Indiana University Health Simon Cancer Center, Indianapolis, Indiana Dana Farber/Harvard Cancer Center, Boston, Massachusetts Karmanos Cancer Institute, Detroit, Michigan Mayo Clinic, Rochester, Minnesota Weill Cornell Medicine/New York Presbyterian Hospital, New York, New York New York Presbyterian Hospital Columbia University Medical Center, New York, New York University of North Carolina at Chapel Hill, Chapel Hill, North Carolina Wake Forest University Health Sciences, Winston-Salem, North Carolina The Ohio State University James Cancer Hospital, Columbus, Ohio University of Texas Southwestern, Dallas, Texas VA Puget Sound Health Care System, Seattle, Washington France
Centre Hospitalier Universitaire (CHU) de Poitiers, Poitiers, New Aquitaine CHU de Lille - Rue Michel Polonovski, Lille, Nord Nantes University Hospital, Nantes, Pays de la Loire Region Centre Hospitalier Universitaire Angers, Angers CHU Montpellier - Departement D'Hematologie, Montpellier Saint Antoine Hospital, Paris Institut Gustave Roussy, Villejuif Hospital Henri Mondor, Créteil, Île-de-France Region Saint Louis Hospital, Paris, Île-de-France Region Hopital Necker, Paris, Île-de-France Region Greece
Evangelismos General Hospital, Athens, Attica General Hospital of Athens Alexandra, Athens Israel
Sheba Medical Center, Ramat Gan, Central District Rambam Health Care Campus, Haifa Hadassah Medical Center, Jerusalem Spain
Hospital Clinico Universitario de Santiago, Santiago de Compostela, A Coruna Hospital Germans Trias i Pujol, Badalona, Barcelona Hospital Universitario Marques de Valdecilla, Santander, Cantabria Hospital Universitario Quiron Salud Madrid, Pozuelo de Alarcón, Madrid Clinica Universidad de Navarra, Pamplona, Navarre Hospital Universitario Vall d'Hebron, Barcelona Hospital Clinic de Barcelona, Barcelona Institut Catala d'Oncologia (ICO) - Hospital Duran i Reynals,, Barcelona Universitaru Hospital La Princesa, Madrid Clinica Universidad de Navarra - Madrid, Madrid Hospital Universitario Ramon y Cajal - Servicio de Psiquiatria, Madrid University Hospital and Research Institute, Madrid Hospital Universitario HM Sanchinarro, Madrid