Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

Recruiting

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Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.

Trial locations(44 sites)

United States

University of Kentucky Chandler Medical Center, Lexington, Kentucky

Norton Cancer Institute, Louisville, Kentucky

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland

MD Anderson Cancer Center, Houston, Texas

NEXT Virginia, Fairfax, Virginia

Australia

Scientia Clinical Research, Randwick, New South Wales

Royal North Shore Hospital, Sydney, New South Wales

Cancer Research SA, Adelaide, South Australia

Monash Health, Clayton, Victoria

Germany

Universitätsklinikum Köln, Cologne

Krankenhaus Nordwest GmbH - Institut Fuer Klinisch-Onkologische Forschung (IKF), Frankfurt

University Medical Center Hamburg-Eppendorf, Hamburg

Universitaetsmedizin der Johannes Gutenberg Universitaet Mainz KoeR, Mainz

Hungary

ICON-PRA Budapest, Fázis 1 Vizsgálóhely, Budapest

Semmelweis Egyetem ÁOK Belgyógyászati és Onkológiai Klinika, Budapest

National Institute of Oncology, Budapest

Clinexpert Ltd, Gyöngyös

Poland

Uniwersyteckie Centrum Kliniczne, Gdansk

Warminsko Mazurskie Centrum Chorob Pluc w Olsztynie, Olsztyn

NZOZ Medpolonia Sp. Z o.o, Poznan

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy, Warsaw

Spain

Institut Catala d'Oncologia Badalona, Hospital Germans Trias I Pujol, Badalona

Hospital Universitario Vall d'Hebron, Barcelona

MD Anderson Cancer Center, Madrid

Hospital Universitario Fundacion Jimenez Diaz, Madrid

START Madrid - CIOCC. Grupo Hospital de Madrid (HM) - Centro Integral Oncologico Clara Campal (CIOCC), Madrid

Complejo Hospitalario Universitario de Santiago de Compostela (CHUS) - Hospital Clinico Universitario (University Clinical Hospital), Santiago de Compostela

Hospital Universitario Virgen Macarena, Seville

Hospital Universitario y Politecnico La Fe, Valencia

Turkey (Türkiye)

Adana City Training and Research Hospital, Adana

Haceteppe Hospital, Ankara

Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara

Ankara City Hospital, Ankara

Koc University Hospital, Istanbul

University Medical Faculty Oncology Institute, Istanbul

Yeditepe University, Istanbul

Ege University School of Medicine Tulay Aktas Oncology Hospital, Izmir

Dokuz Eylul Medical School, Izmir

United Kingdom

Cambridge University Hospitals NHS Foundation Trust, Cambridge

Velindre NHS Trust, Cardiff

The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool

Guy's and St Thomas NHS Foundation Trust, London

University College London Hospitals NHS Foundation Trust, London

The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne