Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

Recruiting

Back to Advanced Malignant Solid Neoplasm trials

Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.

Trial locations(182 sites)

United States

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

University of South Alabama Mitchell Cancer Institute, Mobile, Alabama

The Angeles Clinic and Research Institute - West Los Angeles Office, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

VA Palo Alto Health Care System, Palo Alto, California

UM Sylvester Comprehensive Cancer Center at Aventura, Aventura, Florida

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida

UM Sylvester Comprehensive Cancer Center at Coral Springs, Coral Springs, Florida

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida

UM Sylvester Comprehensive Cancer Center at Hollywood, Hollywood, Florida

Mayo Clinic in Florida, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

UM Sylvester Comprehensive Cancer Center at Kendall, Miami, Florida

UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho

Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho

Saint Luke's Cancer Institute - Meridian, Meridian, Idaho

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho

Saint Luke's Cancer Institute - Nampa, Nampa, Idaho

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho

Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho

Advocate Good Shepherd Hospital, Barrington, Illinois

John H Stroger Jr Hospital of Cook County, Chicago, Illinois

University of Illinois, Chicago, Illinois

Advocate Illinois Masonic Medical Center, Chicago, Illinois

AMG Crystal Lake - Oncology, Crystal Lake, Illinois

Carle at The Riverfront, Danville, Illinois

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Advocate Good Samaritan Hospital, Downers Grove, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Advocate Sherman Hospital, Elgin, Illinois

Advocate South Suburban Hospital, Hazel Crest, Illinois

AMG Libertyville - Oncology, Libertyville, Illinois

Condell Memorial Hospital, Libertyville, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Loyola University Medical Center, Maywood, Illinois

Carle BroMenn Medical Center, Normal, Illinois

Carle Cancer Institute Normal, Normal, Illinois

Cancer Care Center of O'Fallon, O'Fallon, Illinois

Advocate Christ Medical Center, Oak Lawn, Illinois

Advocate Outpatient Center - Oak Lawn, Oak Lawn, Illinois

Advocate High Tech Medical Park, Palos Heights, Illinois

Advocate Lutheran General Hospital, Park Ridge, Illinois

Memorial Hospital East, Shiloh, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Springfield Clinic, Springfield, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Carle Cancer Center, Urbana, Illinois

UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa

UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Waukee Clinic, Waukee, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Lafayette Family Cancer Center-EMMC, Brewer, Maine

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

National Institutes of Health Clinical Center, Bethesda, Maryland

Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan

Trinity Health Medical Center - Brighton, Brighton, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan

Trinity Health Medical Center - Canton, Canton, Michigan

Chelsea Hospital, Chelsea, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan

Corewell Health Dearborn Hospital, Dearborn, Michigan

Corewell Health Farmington Hills Hospital, Farmington Hills, Michigan

Cancer Hematology Centers - Flint, Flint, Michigan

Genesee Hematology Oncology PC, Flint, Michigan

Genesys Hurley Cancer Institute, Flint, Michigan

Hurley Medical Center, Flint, Michigan

University of Michigan Health - Sparrow Lansing, Lansing, Michigan

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan

Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan

Corewell Health Children's, Royal Oak, Michigan

Corewell Health William Beaumont University Hospital, Royal Oak, Michigan

MyMichigan Medical Center Saginaw, Saginaw, Michigan

Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan

MyMichigan Medical Center Tawas, Tawas City, Michigan

Corewell Health Beaumont Troy Hospital, Troy, Michigan

Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan

Huron Gastroenterology PC, Ypsilanti, Michigan

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan

Essentia Health - Deer River Clinic, Deer River, Minnesota

Essentia Health Cancer Center, Duluth, Minnesota

Essentia Health Hibbing Clinic, Hibbing, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

Essentia Health Sandstone, Sandstone, Minnesota

Essentia Health Virginia Clinic, Virginia, Minnesota

Saint Francis Medical Center, Cape Girardeau, Missouri

Siteman Cancer Center at Saint Peters Hospital, City of Saint Peters, Missouri

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri

Washington University School of Medicine, St Louis, Missouri

Siteman Cancer Center-South County, St Louis, Missouri

Siteman Cancer Center at Christian Hospital, St Louis, Missouri

Community Hospital of Anaconda, Anaconda, Montana

Billings Clinic Cancer Center, Billings, Montana

Bozeman Health Deaconess Hospital, Bozeman, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Logan Health Medical Center, Kalispell, Montana

Community Medical Center, Missoula, Montana

OptumCare Cancer Care at Seven Hills, Henderson, Nevada

OptumCare Cancer Care at Charleston, Las Vegas, Nevada

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Roswell Park Cancer Institute, Buffalo, New York

NYU Langone Hospital - Long Island, Mineola, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Columbus Oncology and Hematology Associates Inc, Columbus, Ohio

Riverside Methodist Hospital, Columbus, Ohio

Grant Medical Center, Columbus, Ohio

Doctors Hospital, Columbus, Ohio

Dayton Physician LLC - Englewood, Dayton, Ohio

Delaware Health Center-Grady Cancer Center, Delaware, Ohio

Grady Memorial Hospital, Delaware, Ohio

Columbus Oncology and Hematology Associates, Dublin, Ohio

Dublin Methodist Hospital, Dublin, Ohio

Kettering Medical Center, Kettering, Ohio

OhioHealth Mansfield Hospital, Mansfield, Ohio

OhioHealth Marion General Hospital, Marion, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon

Providence Portland Medical Center, Portland, Oregon

Providence Saint Vincent Medical Center, Portland, Oregon

ECOG-ACRIN Cancer Research Group, Philadelphia, Pennsylvania

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

Asplundh Cancer Pavilion, Willow Grove, Pennsylvania

Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina

Prisma Health Cancer Institute - Easley, Easley, South Carolina

Prisma Health Cancer Institute - Butternut, Greenville, South Carolina

Prisma Health Cancer Institute - Faris, Greenville, South Carolina

Prisma Health Cancer Institute - Eastside, Greenville, South Carolina

Prisma Health Cancer Institute - Greer, Greer, South Carolina

Prisma Health Cancer Institute - Seneca, Seneca, South Carolina

Rapid City Regional Hospital, Rapid City, South Dakota

Bristol Regional Medical Center, Bristol, Tennessee

Regional Cancer Center at Johnson City Medical Center, Johnson City, Tennessee

Ballad Health Cancer Care - Kingsport, Kingsport, Tennessee

Wellmont Holston Valley Hospital and Medical Center, Kingsport, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Scott and White Memorial Hospital, Temple, Texas

Ballad Health Cancer Care - Bristol, Bristol, Virginia

University of Virginia Cancer Center, Charlottesville, Virginia

VCU Massey Cancer Center at Stony Point, Richmond, Virginia

VCU Massey Comprehensive Cancer Center, Richmond, Virginia

Swedish Medical Center-First Hill, Seattle, Washington

West Virginia University Charleston Division, Charleston, West Virginia

ThedaCare Regional Cancer Center, Appleton, Wisconsin

Duluth Clinic Ashland, Ashland, Wisconsin

ThedaCare Cancer Care - Berlin, Berlin, Wisconsin

Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin

Aurora Saint Luke's South Shore, Cudahy, Wisconsin

Aurora Health Care Germantown Health Center, Germantown, Wisconsin

Aurora Cancer Care-Grafton, Grafton, Wisconsin

Aurora BayCare Medical Center, Green Bay, Wisconsin

Mercyhealth Hospital and Cancer Center - Janesville, Janesville, Wisconsin

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin

Gundersen Lutheran Medical Center, La Crosse, Wisconsin

University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin

Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin

Aurora Sinai Medical Center, Milwaukee, Wisconsin

ThedaCare Regional Medical Center - Neenah, Neenah, Wisconsin

ThedaCare Cancer Care - New London, New London, Wisconsin

ThedaCare Cancer Care - Oshkosh, Oshkosh, Wisconsin

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin

Aurora Cancer Care-Racine, Racine, Wisconsin

ThedaCare Cancer Care - Shawano, Shawano, Wisconsin

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin

Aurora Medical Center in Summit, Summit, Wisconsin

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin

ThedaCare Cancer Care - Waupaca, Waupaca, Wisconsin

Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin

Aurora West Allis Medical Center, West Allis, Wisconsin