Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma

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Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma — Stella

Home/Clinical Stage II Esophageal Adenocarcinoma AJCC v8/

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Recruiting

Back to Clinical Stage II Esophageal Adenocarcinoma AJCC v8 trials

Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.

Trial locations(1 site)

United States

Roswell Park Cancer Institute, Buffalo, New York

Key details

Phase

Safety & dosing

Sponsor

Roswell Park Cancer Institute

Collaborators

United States Department of Defense

Enrollment target

~40 participants

Started

March 2023

Primary completion

March 2029

Age range

18 Years and older

Last updated December 2025

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