A Study to Evaluate the Pharmacokinetics and Safety of Loncastuximab Tesirine in Participants With Relapsed or Refractory Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma With Hepatic Impairment (LOTIS-10)

Recruiting

Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.

Trial locations(14 sites)

United States

The Oncology Institute of Hope & Innovation - Lynwood, Lynwood, California

Brazil

Hospital Sírio-Libanês - Brasília, Brasília

Hospital Mãe de Deus - Centro Integrado de Oncologia, Porto Alegre

Hospital Sírio-Libanês - São Paulo, São Paulo

A Beneficência Portuguesa de São Paulo - Unidade Mirant, São Paulo

Hospital 9 de Julho, São Paulo

Albert Einstein Israelite Hospital, São Paulo

South Korea

Kyungpook National University Chilgok Hospital, Daegu, Daegu Gwang'yeogsi

Dong-A University Hospital, Pusan, Gyeongsangnam-do

Korea University Anam Hospital, Seoul, Seongbuk District

Seoul National University Hospital, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi]

Severance Hospital, Seoul, Seoul Teugbyeolsi

Taiwan

National Taiwan University Hospital, Taipei

Koo Foundation Sun Yat-Sen Cancer Center, Taipei