Plain-English translation of NCT05685173 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new combination of two experimental medications called and in patients with aggressive B-cell lymphoma. These medications are designed to work together to help the immune system recognize and fight cancer cells. The study will first find the safest dose, then test how well the medication works.
Many patients with aggressive B-cell lymphoma eventually stop responding to standard treatments. This trial is exploring whether this new combination approach might offer hope for patients whose cancer has returned or is no longer responding to previous therapies.
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The trial has two phases. In the first phase, researchers gradually increase the dose of the medication to find the safest amount. In the second phase, participants receive the safe dose identified in phase one. Throughout the study, you will have regular clinic visits for blood tests, scans, and physical exams to check how you're tolerating the treatment and how well it's working.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States