Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.
(71 sites) United States
City of Hope National Medical Center, Duarte, California City of Hope - Seacliff, Huntington Beach, California City of Hope at Irvine Lennar, Irvine, California UCSD Moores Cancer Center, La Jolla, California City of Hope - Long Beach Elm, Long Beach, California Yale Cancer Center, New Haven, Connecticut Florida Cancer Specialists - SOUTH - SCRI - PPDS, Fort Myers, Florida Florida Cancer Specialists - NORTH - SCRI - PPDS, St. Petersburg, Florida Florida Cancer Specialists - EAST - SCRI - PPDS, West Palm Beach, Florida NYU Langone Hospital - Long Island, Mineola, New York NYU Cancer Center, New York, New York Mount SInai Medical Center, New York, New York Montefiore Medical Center - Montefiore Medical Park, The Bronx, New York MD Anderson Cancer Center, Houston, Texas Oncology & Hematology Associates of Southwest Virginia, Inc, Blacksburg, Virginia Virginia Oncology Associates, Norfolk, Virginia Argentina
Hospital Britanico, Buenos Aires Clinica Adventista Belgrano, Ciudad Autonoma Buenos Aires Centro Oncologico Riojano Integral (CORI), La Rioja Australia
Concord Repatriation General Hospital, Concord, New South Wales Peter MacCallum Cancer Centre, Melbourne, Victoria Alfred Health, Melbourne, Victoria Belgium
Cliniques Universitaires St-Luc, Brussels Jessa Zkh (Campus Virga Jesse), Hasselt Clinique Ste-Elisabeth, Namur AZ Delta (Campus Rumbeke), Roeselare Brazil
Hospital de Cancer de Barretos, Barretos, São Paulo Instituto do Cancer do Estado de Sao Paulo - ICESP, São Paulo, São Paulo Canada
Ottawa Hospital Regional Cancer Centre, Ottawa, Ontario Princess Margaret Cancer Center, Toronto, Ontario Jewish General Hospital, Montreal, Quebec China
Hunan Cancer Hospital, Changsha Harbin Medical University Cancer Hospital, Harbin Shanghai Pulmonary Hospital, Shanghai Israel
Rambam Medical Center, Haifa Tel Aviv Sourasky Medical Ctr, Tel Aviv Italy
Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Campania Policlinico Universitario Agostino Gemelli IRCCS, Rome, Lazio Irccs Istituto Nazionale Dei Tumori (Int), Milan, Lombardy A.O. Universitaria S. Luigi Gonzaga, Orbassano, Piedmont Japan
National Cancer Center Hospital East, Chiba Kindai University Hospital, Osaka National Cancer Center Hospital, Tokyo The Cancer Institute Hospital of JFCR, Tokyo Wakayama Medical University Hospital, Wakayama Netherlands
NKI The Netherlands Cancer Institute, Amsterdam Poland
Uniwersyteckie Centrum Kliniczne, Gda?sk Krakowski Szpital Specjalistyczny im sw. Jana Paw?a II, Krakow Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie, Olsztyn South Korea
Pusan National University Hospital, Busan Seoul National University Hospital, Seoul Asan Medical Center, Seoul Samsung Medical Center, Seoul Korea University Guro Hospital, Seoul Spain
ICO Badalona-H.U. Germans Trias i Pujol, Badalona, Barcelona Vall d?Hebron Institute of Oncology (VHIO), Barcelona, Barcelona Hospital General Universitario Gregorio Marañon, Madrid Hospital Universitario 12 de Octubre, Madrid Hospital Universitario Virgen del Rocio, Seville Hospital Clinico Universitario de Valencia, Valencia Sweden
Sahlgrenska University Hospital, Gothenburg Switzerland
Universitätsspital Basel, Basel Taiwan
Taichung Veterans General Hospital, Taichung National Cheng Kung University Hospital, Tainan National Taiwan Uni Hospital, Taipei Chang Gung Medical Foundation - Linkou, Taoyuan District United Kingdom
Beatson West of Scotland Cancer Centre, Glasgow Barts & London School of Med, London