Recruiting

A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.

Trial locations(70 sites)

United States

City of Hope - Duarte Main Site, Duarte, California

Maryland Oncology Hematology - Independent of SCRI/ US Oncology, Columbia, Maryland

Weill Cornell Medicine NewYork-Presbyterian, New York, New York

Duke University, Durham, North Carolina

Cleveland Clinic, Cleveland, Ohio

MD Anderson, Houston, Texas

Huntsman Cancer Institute, Salt Lake City, Utah

Belgium

UZ Gent, Ghent

UZ Leuven - Campus Gasthuisberg, Leuven

Bulgaria

University Multiprofile Hospital for Active Treatment Sveti George - Base 1, Plovdiv

University Hospital Sv.Ivan Rilski - Sofia, Sofia

University Multiprofile Hospital for Active Treatment Aleksandrovska, Sofia

Specialized Hospital for Active Treatment of Hematological Diseases - EAD Sofia, Sofia

University Multiprofile Hospital for Active Treatment - Prof. Dr. Stoyan Kirkovich AD Department of Clinical Hematology, Stara Zagora

Canada

Research Institute of the McGill University Health Centre, Montreal, Quebec

Czechia

Fakultní nemocnice Olomouc, Olomouc

Denmark

Aarhus Universitetshospital, Aarhus N, Central Jutland

France

Institut Bergonié, Bordeaux, Aquitaine

Centre Hospitalier Lyon-Sud, Pierre-Bénite, Auvergne-Rhône-Alpes

CHU Tours, Hôpital Bretonneau Service d'Hématologie thérapie cellulaire, Tours, Indre-et-Loire

Chu De Nîmes - Institut De Cancérologie Du Gard, Nîmes, Occitanie

Centre Hospitalier Universitaire d'Angers, Angers, Pays de la Loire Region

Hôpital Saint-Louis, Paris

Hôpital Cochin, Paris

Centre Hospitalier Universitaire de Saint-Etienne, Saint-Priest-en-Jarez

Germany

Marien Hospital Düsseldorf, Düsseldorf

University Hospital Jena, Jena

Greece

Laiko General Hospital of Athens, Athens, Attica

University General Hospital Attikon, Athens, Attica

"Georgios Papanikolaou" General Hospital of Thessaloniki, Thessaloniki, Central Macedonia

University General Hospital of Ioannina, Hematology Department, Ioannina, Epirus

University General Hospital of Larissa, Hematology Department, Larissa, Thessaly

Hungary

Semmelweis Egyetem, Budapest

Israel

Tel Aviv Sourasky Medical Center, Tel Aviv, Tel Aviv

Rambam Health Care Campus, Haifa

Carmel Medical Center, Haifa

Italy

Fondazione IRCCS Cà Granda - Ospedale Maggiore Policlinico, Milan, Milan

Hematology Division, Mauriziano Hospital, University of Turin, Orbassano, Torino

Azienda Ospedaliero-Universitaria Citta della Salute e della Scienza di Torino, Torino, Turin

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna

IRCCS Ospedale Policlinico San Martino, Genova

Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST, Meldola

Istituto Europeo di Oncologia, Milan

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milan

Azienda Ospedaliero-Universitaria Maggiore della Carità di Novara, Novara

Fondazione IRCCS Policlinico San Matteo, Pavia

Università Campus Bio-Medico di Roma, Rome

Netherlands

Spaarne Gasthuis, Hoofddorp

Poland

Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin

AIDPORT, Skórzewo

Medicover Clinical Integrated Systems Sp. z o.o., Torun

Romania

Coltea - Spital Clinic, Bucharest

Spitalul Filantropia - Craiova, Craiova

Institutul Regional de Oncologie Iasi, Iași

South Korea

Seoul St. Mary's Hospital, The Catholic University of Korea, Seocho, Seoul

Seoul National University Hospital, Seoul, Seoul Teugbyeolsi

Severance Hospital, Seoul, Seoul Teugbyeolsi

Pusan National University Hospital, Busan

Spain

Hospital Germans Trias i Pujol, Badalona, Barcelona

Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, Murcia

Hospital Universitario Central de Asturias, Oviedo, Principality of Asturias

Hospital San Pedro de Alcantara, Cáceres

Institut Català d'Oncologia Girona, Girona

Hospital Universitario de Gran Canaria Doctor Negrin, Las Palmas de Gran Canaria

Complejo Asistencial Universitario de Salamanca - Hospital Clínico, Salamanca

Hospital Clínico Universitario de Valencia, Valencia

Taiwan

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City

National Taiwan University Hospital, Taipei

Taoyuan Chang Gung Memorial Hospital, Taoyuan District

United Kingdom

Guy's and Saint Thomas' NHS Foundation Trust, London