A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer — Stella
Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.
(120 sites) United States
Alaska Women's Cancer Care, Anchorage, Alaska Yale University School of Medicine, New Haven, Connecticut Sylvester Comprehensive Cancer Center at Lennar, Coral Gables, Florida Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida Florida Cancer Specialists, Lake Mary, Florida Sylvester Cancer Center, Miami, Florida Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida Community MD Anderson Cancer Center- East, Indianapolis, Indiana Community MD Anderson Cancer Center- South, Indianapolis, Indiana Community Health Network - MD Anderson, Indianapolis, Indiana St. Elizabeth Medical Center, Edgewood, Kentucky Washington University School of Medicine Obstetrics and Gynecology, St Louis, Missouri Valley Health System, Paramus, New Jersey Holy Name, Teaneck, New Jersey NHPP Imbert, Bay Shore, New York Northwell Health, LLC PRIME, Lake Success, New York Perlmutter Cancer Center at NYU Langone Hospital- Long Island, Mineola, New York NYU Langone Health, New York, New York NHPP LHH, New York, New York Duke Women's Cancer Care- Raleigh, Durham, North Carolina Duke Cancer Center, Durham, North Carolina Ohio State University Wexner Medical Center, Hilliard, Ohio University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma Oklahoma Cancer Specialists and Research Institute, Tulsa, Oklahoma Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania Medical University of South Carolina (MUSC), Charleston, South Carolina Sanford Cancer Center Gynecologic Oncology, Sioux Falls, South Dakota Texas Oncology-Bedford, Bedford, Texas Houston Area Locations- Woodlands, Conroe, Texas Texas Oncology-Presbyterian Cancer Center Dallas, Dallas, Texas Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, Texas Texas Oncology Paris, Fort Worth, Texas Houston Methodist Hospital, Houston, Texas University of Texas - MD Anderson, Houston, Texas Houston Area Locations- Sugar Land, Houston, Texas Houston Area Locations- West Houston, Houston, Texas Houston Area Locations- League City, League City, Texas University of Washington - Seattle Cancer Care Alliance, Seattle, Washington Australia
GenesisCare St Andrews Hospital, Adelaide GenesisCare North Shore (Oncology), St Leonards Canada
McGill University Health Centre/Glen Site / Royal Victoria Hospital, Montreal University Health Network - Princess Margaret Cancer Centre, Toronto China
Beijing Cancer Hospital, Beijing Chongqing Cancer Hospital, Chongqing Fujian Provincial Cancer Hospital, Fuzhou The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Zhejiang Cancer Hospital, Hangzhou Shandong Cancer Hospital, Jinan Qilu Hospital of Shandong University, Jinan Guangxi Medical University Cancer Hospital, Nanning Fudan University Shanghai Cancer Center, Shanghai National Cheng Kung University Hospital, Tainan Tianjin Medical University Cancer Institute & Hospital, Tianjin Hubei Cancer Hospital, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan Czechia
Fakultni nemocnice Hradec Kralove, Hradec Králové Fakultni nemocnice v Motole, Prague Fakultni nemocnice Bulovka, Prague Vseobecna fakultni nemocnice v Praze, Prague France
Institut Bergonié, Bordeaux Centre Francois Baclesse, Caen Centre Jean Perrin - CLCC, Clermont-Ferrand Centre Georges François Leclerc, Dijon Institut Paoli Calmettes, Marseille Institut du Cancer de Montpellier, Montpellier Hôpital Privé du Confluent, Nantes Groupe Hospitalier Diaconesses - Hôpital De La Croix Saint Simon, Paris CARIO - Centre Armoricain de Radiothérapie, Imagerie médicale et Oncologie, Plérin Institut Curie, Saint-Cloud ICL Alexis Vautrin, Vandœuvre-lès-Nancy Germany
Kliniken Essen-Mitte, Essen Universitaetsklinikum Mannheim, Mannheim Universitaetsklinikum Ulm, Ulm Italy
IRCCS Centro di Riferimento Oncologico, Aviano Azienda Ospedaliera Per Lemergenza Cannizzaro, Catania Azienda Ospedaliera Universitaria Careggi, Florence Humanitas San Pio X, Milan IEO Istituto Europeo di Oncologia, Milan Istituto Nazionale Tumori Fondazione G. Pascale, Naples Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma Istituto Clinico Humanitas, Rozzano Ospedale Mauriziano Umberto I, Torino Japan
National Cancer Center Hospital, Chūōku NHO Kyushu Cancer Center, Fukuoka Saitama Medical University International Medical Center, Hidaka-shi National Cancer Center Hospital East, Kashiwa-shi Cancer Institute Hospital of JFCR, Kōtoku Jikei University Hospital, Minatoku Shizuoka Cancer Center, Nagaizumi-cho Aichi Cancer Center Hospital, Nagoya Niigata Cancer Center Hospital, Niigata Osaka International Cancer Institute, Osaka Hokkaido University Hospital, Sapporo Iwate Medical University Hospital, Shiwa-gun Poland
Uniwersyteckie Centrum Kliniczne, Gdansk Mazowiecki Szpital Wojewodzki w Siedlcach Sp z o o, Siedlce Portugal
Hospital Professor Doutor Fernando Fonseca, E.P.E., Amadora South Korea
National Cancer Center, Goyang-si CHA Bundang Medical Center, CHA University, Seongnam-si National University Hospital, Seoul Severance Hospital, Yonsei University Health System, Seoul Asan Medical Center, Seoul Samsung Medical Center, Seoul The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul Spain
Hospital Clinic de Barcelona, Barcelona Hospital Universitari Vall d'Hebron, Barcelona Hospital Universitario Ciudad de Jaen, Jaén Hospital Universitario Clinico San Carlos, Madrid Hospital Universitario 12 de Octubre, Madrid Hospital Universitario La Paz, Madrid Clinica Universidad de Navarra (MAD), Pamplona Clinica Universidad de Navarra, Pamplona Hospital Clínico Universitario Valencia, Valencia Taiwan
Taichung Veterans General Hospital, Taichung Taipei Veterans General Hospital, Taipei Koo Foundation Sun Yat-Sen Cancer Center, Taipei Chang Gung Memorial Hospital,Linkou, Taoyuan United Kingdom
Royal United Hospital, Bath Key details Phase
Safety & dosing / Large-scale testing
Collaborators
Merck Sharp & Dohme LLC
Enrollment target
~860 participants
Primary completion
February 2028
Last updated January 2026