A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast — Stella
Phase 3 — Large-scale testing across thousands of people, comparing the new treatment against current standard treatments.
(371 sites) United States
University of Alabama at Birmingham, Birmingham, Alabama University of Arizona, Tucson, Arizona University of Southern California, Los Angeles, California Cedars-Sinai Medical Center, Los Angeles, California University of California Los Angeles, Los Angeles, California University of California Davis, Sacramento, California National Jewish Health, Denver, Colorado Yale University School of Medicine, New Haven, Connecticut Christiana Hospital, Newark, Delaware Georgetown University, Washington D.C., District of Columbia St. Francis Medical Institute, Clearwater, Florida University of Florida, Gainesville, Florida Clinical Research Specialists LLC - Kissimmee, Kissimmee, Florida Advanced Pulmonary Research Institute, Loxahatchee Groves, Florida Piedmont Physicians Pulmonary & Sleep Medicine of Buckhead, Atlanta, Georgia The Emory Clinic, Atlanta, Georgia Northshore University Health System, Evanston, Illinois University of Kansas Medical Center, Kansas City, Kansas Tulane Medical Center, New Orleans, Louisiana Johns Hopkins Hospital, Baltimore, Maryland Massachusetts General Hospital, Boston, Massachusetts Brigham and Women's Hospital, Boston, Massachusetts St. Elizabeth's Medical Center, Boston, Massachusetts Beth Israel Deaconess Medical Center, Boston, Massachusetts University of Michigan, Ann Arbor, Michigan Corewell Health William Beaumont University Hospital, Royal Oak, Michigan University of Minnesota, Minneapolis, Minnesota Mayo Clinic, Rochester, Rochester, Minnesota The Lung Research Center, LLC, Chesterfield, Missouri Creighton University, Omaha, Nebraska University of Nebraska Medical Center, Omaha, Nebraska Renown Regional Medical Center, Reno, Nevada Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire Northern Westchester Hospital, Mount Kisco, New York Columbia University Medical Center-New York Presbyterian Hospital, New York, New York NewYork-Presbyterian/Weill Cornell Medical Center, New York, New York Duke University Medical Center, Durham, North Carolina Southeastern Research Center-Winston Salem-69289, Winston-Salem, North Carolina University of Cincinnati, Cincinnati, Ohio Cleveland Clinic, Cleveland, Ohio The Ohio State University Wexner Medical Center, Columbus, Ohio The Oregon Clinic, Portland, Oregon University of Pennsylvania, Philadelphia, Pennsylvania Temple University Hospital, Philadelphia, Pennsylvania Allegheny General Hospital, Pittsburgh, Pennsylvania Infinity Medical Research, Inc., East Providence, Rhode Island Lowcountry Lung and Critical Care, Charleston, South Carolina Clinical Trials Center of Middle Tennessee, LLC, Franklin, Tennessee Vanderbilt University Medical Center, Nashville, Tennessee Baylor University Medical Center, Dallas, Texas UT Health San Antonio, San Antonio, Texas Intermountain Medical Center-Murray-69497, Murray, Utah University of Utah Health Sciences Center, Salt Lake City, Utah University of Vermont, Burlington, Vermont Inova Fairfax Hospital, Falls Church, Virginia Virginia Mason Medical Center, Seattle, Washington University of Wisconsin, Madison, Wisconsin Argentina
Centro de Investigaciones Metabolicas (CINME)-C.A.B.A-61553, C.a.b.a CEDIC - Centro de Investigacion Clinica, CABA Hospital Italiano de Buenos Aires, CABA Consultorios Médicos del Buen Ayre, Capital Federal CEMER-Centro Medico De Enfermedades Respiratorias, Florida Instituto Ave Pulmo - Fundacion Enfisema, Mar del Plata Centro Respiratorio de Quilmes, Quilmes Instituto Médico de la Fundación Estudios Clínicos, Rosario Australia
Canberra Hospital, Garran, Australian Capital Territory Royal Prince Alfred Hospital, Camperdown, New South Wales Westmead Hospital, Westmead, New South Wales Lung Research Queensland, Chermside, Queensland The Prince Charles Hospital, Chermside, Queensland Royal Adelaide Hospital, Adelaide, South Australia Austin Hospital, Heidelberg, Victoria The Alfred Hospital, Melbourne, Victoria Fiona Stanley Hospital, Murdoch, Western Australia Trialswest, Spearwood, Western Australia Macquarie University, Macquarie Park Austria
Krems University Hospital, Krems LKH Salzburg University Hospital, Salzburg AKH - Medical University of Vienna, Vienna Clinic Floridsdorf, Vienna Klinikum Wels - Grieskirchen GmbH, Wels Belgium
Ziekenhuis Netwerk Antwerpen (ZNA) - Campus Middelheim, Antwerp ULB Hopital Erasme, Brussels Cliniques Universitaires Saint-Luc, Brussels Universitair Ziekenhuis Gent, Ghent Centre Hospitalier Universitaire de Liège, Liège Yvoir - UNIV UCL de Mont-Godinne, Yvoir Brazil
Serviços Medicos Respirar Sul Fluminense, Barra Mansa Hospital das Clinicas da Universidade Federal de Minas Gerais (HCUFMG), Belo Horizonte,Minas Gerais SAPIENS - Instituto de Estudos e Pesquisa Clínica, Curitiba CLARE - Clinica de Pneumologia, Goiânia Irmandade Santa Casa de Misericordia de Porto Alegre, Porto Alegre Hospital Nossa Senhora da Conceição, Porto Alegre - RS CEMEC - Centro Multidisciplinar de Estudos Clínicos, São Bernardo do Campo Hospital Alemao Oswaldo Cruz, São Paulo Hospital das Clinicas da Faculdade de Medicina da USP, São Paulo Canada
University of Alberta Hospital (University of Alberta), Edmonton, Alberta Kelowna Respirology & Allergy Research, Kelowna, British Columbia St. Paul's Hospital (Vancouver), Vancouver, British Columbia Vancouver General Hospital, Vancouver, British Columbia Dr. Georges-L.-Dumont University Hospital Centre, Moncton, New Brunswick QEII Health Sciences Centre, Halifax, Nova Scotia St. Joseph's Healthcare Hamilton, Hamilton, Ontario Dr. Syed Anees Medicine Professional Corporation, Windsor, Ontario Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal, Quebec McGill University Health Centre (MUHC), Montreal, Quebec CIC Mauricie (Trois Rivieres), Trois-Rivières, Quebec Royal University Hospital (Saskatoon), Saskatoon, Saskatchewan Chile
Instituto Nacional del Tórax, Providencia, Santiago de Chile Centro de Investigación del Maule, Talca China
Beijing Chao-Yang Hospital, Beijing China-Japan Friendship Hospital, Beijing Peking Union Medical College Hospital, Beijing The Second Xiangya Hospital Of Central South University, Changsha West China Hospital, Sichuan University, Chengdu People's Hospital of Sichuan Province, Chengdu First Affiliated Hospital of Guangzhou Medical University, Guangzhou NanFang Hosptial, Guangzhou Hangzhou First People's Hospital, Hangzhou The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou Zhejiang Hospital, Hangzhou Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine, Hangzhou Anhui Provincial Hospital, Hefei
Croatia
University hospital center Zagreb, Zagreb University Hospital Dubrava, Zagreb Solmed Polyclinic, Zagreb Czechia
University Thomayer´s Hospital, Prague Denmark
Gentofte Hospital, Hellerup Odense University Hospital, Odense C Estonia
North Estonia Medical Centre Foundation, Tallinn, Tallinn Finland
HYKS Keuhkosairauksien tutkimusyksikkö, Helsinki Oulun yliopistollinen keskussairaala, Oulu Tampere University Hospital, Tampere France
HOP de la Cavale Blanche, Brest Hôpital Louis Pradel, Bron HOP François Mitterrand, Dijon HOP Michallon, La Tronche HOP Bicêtre, Le Kremlin-Bicêtre HOP Paris Saint-Joseph, Paris HOP Européen G. Pompidou, Paris Georgia
National Center for Tuberculosis and Lung Diseases, Tbilisi, Tbilisi LTD The First Medical Center, Tbilisi Germany
Velocity Clinical Research Germany GmbH, Ahrensburg, Ahrensburg CIMS Studienzentrum Bamberg GmbH, Bamberg Vivantes Netzwerk für Gesundheit GmbH, Berlin Universitätsklinikum Bonn AöR, Bonn Fachkrankenhaus Coswig GmbH, Coswig Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH, Essen Universitätsklinikum Hamburg, Eppendorf, Hamburg Klinikum Region Hannover GmbH, Hanover Medizinische Hochschule Hannover, Hanover Thoraxklinik-Heidelberg gGmbH am Universitätsklinikum Heidelberg, Heidelberg Lungenklinik Hemer, Hemer Lungenfachklinik Immenhausen, Immenhausen Klinikum Konstanz, Konstanz Greece
Hospital of Heraklion (PAGNI), Heraklion Univ. Gen. Hosp. of Ioannina, Ioannina Univ. Gen. Hosp. of Patras, Pátrai General Hospital of Thessaloniki "Hippokrateio", Thessaloniki Hungary
Koranyi National Institute For Pulmonolgy, Budapest University of Debrecen Clinical Centre, Debrecen India
P.D. Hinduja National Hospital, Mumbai Ireland
Connolly Hospital Blanchardstown, Dublin Israel
Shamir Medical Center (Assaf Harofeh), Beer Yaakov Lady Davis Carmel Medical Center, Haifa Shaare Zedek Medical Center, Jerusalem 91031, Jerusalem Sourasky Medical Center, Tel Aviv Italy
ASST degli Spedali Civili di Brescia, Brescia A.O.U. Policlinico Vittorio Emanuele, Catania A. O. Universitaria Careggi, Florence Ospedale Colonnello D Avanzo, Foggia Ospedale G.B. Morgagni, Forlì Ospedale San Paolo-MILANO-18793, Milan Ospedale Classificato San Giuseppe, Milan Azienda Ospedaliero-Universitaria di Modena, Modena A.O. San Gerardo di Monza, Monza Azienda Ospedaliera Universitaria di Padova, Padova Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma Ospedali Riuniti di Ancona, Torrette Di Ancona (Ancona) Japan
Tosei General Hospital, Aichi, Seto Chiba University Hospital, Chiba, Chiba University of Fukui Hospital, Fukui, Yoshida-gun National Hospital Organization Kyushu Medical Center, Fukuoka, Fukuoka Kyushu University Hospital, Fukuoka, Fukuoka Aso Co.,Ltd Iizuka Hospital, Fukuoka, Iizuka Hospital of the University of Occupational and Environmental Health, Fukuoka, Kitakyushu Kurume University Hospital, Fukuoka, Kurume Fukushima Medical University Hospital, Fukushima, Fukushima Tsuboi Hospital, Fukushima, Koriyama Hiroshima Prefectural Hospital, Hiroshima, Hiroshima Sapporo Medical University Hospital, Hokkaido, Sapporo Hokkaido University Hospital, Hokkaido, Sapporo
Malaysia
Hospital Pulau Pinang-Pulau Pinang-21953, George Town Hospital Sultan Idris Shah Serdang, Kajang Institut Perubatan Respiratori, Kuala Lumpur Sarawak General Hospital, Kuching Mexico
Centro de Investigacion Integral MEDIVEST S.C, Chihuahua City CREPID Aire y Salud Integral, Coyoacán Centro de Investigacion Farmacologica del Bajío, S.C., León Centro Respiratorio de Mexico, Mexico City Centro de Prevención y Rehabilitación de Enfermedades Pulmon, Monterrey Oaxaca Site Management Organization, S.C., Oaxaca City Netherlands
Zuyderland Medisch Centrum, HEERLENHeerlen Leids Universitair Medisch Centrum (LUMC), Leiden St. Antonius Ziekenhuis, Nieuwegein Erasmus Medisch Centrum-ROTTERDAM-50697, Rotterdam New Zealand
Aotearoa Clinical Trials, Papatoetoe, Auckland Waikato Hospital, Hamilton Greenlane Clinical Centre, One Tree Hill, Auckland Tauranga Hospital, Tauranga South Norway
Haukeland Universitetssykehus, Bergen Akershus Universitetssykehus HF, Nordbyhagen Oslo Universitetssykehus HF, Rikshospitalet, Oslo Poland
University Clinical Center, Gdansk, Gdansk Leszek Giec Upper-Silesian Med.Cent.Silesian Med.Univ., Katowice Przychodnia Alergologiczno-Pulmonologiczna Alergopneuma Sp. z o.o., Świdnik Nat.Instit.of Tuberculosis&LungDiseases,Outpat.Clin,warszawa, Warsaw University Clinical Center of the Medical University of Warsaw, Warsaw Portugal
CHUC - Centro Hospitalar e Universitário de Coimbra, EPE, Coimbra ULS de São José, E.P.E., Lisbon USLM, EPE - Hospital Pedro Hispano, Matosinhos Municipality Centro Hospitalar Vila Nova de Gaia/Espinho, E.P.E, Vila Nova de Gaia Saudi Arabia
King Abdullah International Medical Research Center, Riyadh Serbia
University Clinical Center of Serbia, Belgrade Institute for Pulmonary Diseases of Vojvodina, Kamenitz University Clinical Center Nis, Niš Singapore
Singapore General Hospital, Singapore Tan Tock Seng Hospital, Singapore Slovenia
Hospital Golnik - Univ. Clinic of Pulmonary and Allergic Diseases, Golnik South Africa
Enhancing Care Foundation NPC, Mount Edgecombe South Korea
The Catholic University of Korea, Bucheon St.Mary's Hospital, Bucheon-si Seoul National University Bundang Hospital, Seongnam Kyung Hee University Hospital, Seoul Seoul National University Hospital, Seoul Severance Hospital, Seoul Soonchunhyang University Hospital Seoul, Seoul Asan Medical Center, Seoul Samsung Medical Center, Seoul Spain
Hospital General Universitario de Alicante, Alicante Hospital del Mar, Barcelona Hospital Universitari Vall d'Hebron, Barcelona Hospital Clínic de Barcelona, Barcelona Hospital de Basurto, Bilbao Hospital Universitario Virgen de la Arrixaca, El Palmar Hospital de Galdakao, Galdakao Hospital Universitario Virgen de las Nieves, Granada Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat Hospital Universitario De La Princesa, Madrid Hospital General Universitario Gregorio Marañón, Madrid Hospital Universitario Infanta Leonor, Madrid Hospital Universitario Ramon Y Cajal, Madrid Sweden
Universitetssjukhuset, Linköping, Linköping Akademiska sjukhuset, Uppsala Switzerland
Universitätsspital Basel, Basel Taiwan
Changhua Christian Hospital, Changhua Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City Taichung Veterans General Hospital, Taichung National Taiwan University Hospital, Taipei Taipei Veterans General Hospital, Taipei Thailand
Siriraj Hospital, Bangkok Noi Srinagarind Hospital, Khon Kaen Maharat Nakhonchiangmai Hospital, Muang Ramathibodi Hospital, Ratchatewi Songklanagarind Hospital, Songkhla Turkey (Türkiye)
Gulhane Training and Research Hospital, Ankara Ankara Universitesi Tip Fakultesi, Ankara Akdeniz Universitesi Tip Fakultesi -ANTALYA-33606, Antalya Istanbul Universitesi Istanbul Tip Fakultesi, Istanbul Gazi Universitesi Tip Fakultesi, Yenimahalle/ANKARA United Kingdom
Aberdeen Royal Infirmary, Aberdeen Queen Elizabeth Hospital Birmingham, Birmingham Southmead Hospital, Bristol Royal Infirmary of Edinburgh, Edinburgh Royal Devon and Exeter Hospital, Exeter Royal Lancaster Infirmary, Lancaster St James's University Hospital, Leeds Royal Brompton Hospital, London Altnagelvin Area Hospital, Londonderry Wythenshawe Hospital, Manchester Churchill Hospital, Oxford Southampton General Hospital, Southampton
Key details Sponsor
Boehringer Ingelheim
Enrollment target
~1,700 participants
Primary completion
April 2027
Age range
18 Years and older
Last updated April 2026
Interested in joining? Institut Universitaire de Cardiologie et de Pneumologie de Quebec (IUCPQ), Québec
The Affiliated Hospital of Inner Mongolia Medical University, Hohhot
The First hospital of Jiaxing, Jiaxing Jinhua Municipal Central Hospital, Jinhua Nanjing Drum Tower Hospital, Nanjing Ningbo Medical Center Lihuili Hospital, Ningbo The First Affiliated Hospital of Ningbo University, Ningbo Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Shanghai Chest Hospital, Shanghai Zhongshan Hospital Affiliated to Fudan University, Shanghai Huadong Hospital affiliated to Fudan University, Shanghai China Shenyang Chest Hospital, Shenyang Shenzhen People's Hospital, Shenzhen The University of Hong Kong-Shenzhen Hospital, Shenzhen The First Affiliated Hospital of Soochow University, Suzhou Tianjin Medical University General Hospital, Tianjin The First Affiliated Hospital of Wenzhou Medical University, Wenzhou Wuhan Union Hospital, Wuhan Tongji Hospital Affiliated Tongji Medical College Huazhong University of S & T, Wuhan Renmin Hospital of Wuhan University, Wuhan Wuxi People's Hospital, Wuxi Second Affiliated Hospital of Xi'an JiaoTong University, Xi'an Affiliated Hospital, Xuzhou Medical college, Xuzhou Yichang Central People's Hospital, Yichang General Hospital of Ningxia Medical University, Yinchuan HOP Bichat, Paris
Hôpital Charles Nicolle, Rouen Hôpital Larrey - CHU de Toulouse, Toulouse Klinikum der Universität München AÖR, München
Klinikum Nürnberg, Nuremberg Krankenhaus Bethanien gGmbH, Solingen Helios Hanseklinikum Stralsund, Stralsund Robert Bosch Gesellschaft für medizinische Forschung mbH, Stuttgart Universitätsklinikum Tübingen, Tübingen National Hospital Organization Himeji Medical Center, Hyogo, Himeji
Kobe City Medical Center General Hospital, Hyogo, Kobe Kobe City Hospital Organization Kobe City Medical Center West Hospital, Hyogo, Kobe Kagawa University Hospital, Kagawa, Kita-gun Kanagawa Cardiovascular and Respiratory Center, Kanagawa, Yokohama Saiseikai Kumamoto Hospital, Kumamoto, Kumamoto Tohoku University Hospital, Miyagi, Sendai Nagasaki University Hospital, Nagasaki, Nagasaki Kindai University Hospital, Osaka, Sakai National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Sakai Osaka Medical and Pharmaceutical University Hospital, Osaka, Takatsuki Saitama Red Cross Hospital, Saitama, Saitama Shimane University Hospital, Shimane, Izumo Hamamatsu University Hospital, Shizuoka, Hamamatsu Jichi Medical University Hospital, Tochigi, Shimotsuke Tokushima University Hospital, Tokushima, Tokushima Juntendo University Hospital, Tokyo, Bunkyo-ku Nippon Medical School Hospital, Tokyo, Bunkyo-ku Toranomon Hospital, Tokyo, Minato-ku Kyorin University Hospital, Tokyo, Mitaka Toho University Omori Medical Center, Tokyo, Ota-ku Tokyo Medical University Hospital, Tokyo, Shinjuku-ku Keio University Hospital, Tokyo, Shinjuku-ku National Center for Global Health and Medicine, Tokyo, Shinjuku-ku Wakayama Medical University Hospital, Wakayama, Wakayama Hospital Universitario 12 de Octubre, Madrid
Hospital Universitario Virgen de la Victoria, Málaga Hospital Central de Asturias, Oviedo Hospital Son Espases, Palma de Mallorca Hospital Quirónsalud Madrid, Pozuelo de Alarcón Hospital Universitario Marqués de Valdecilla, Santander Hospital Clínico de Santiago, Santiago de Compostela Hospital Virgen del Rocío, Seville Hospital Nuestra Señora de Valme, Seville Hospital General Universitario de Valencia, Valencia