A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy — Stella
Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.
(18 sites) United States
Children's Hospital of Alabama, Birmingham, Alabama Children's Hospital of Orange County, Orange, California UCSF Medical Center-Mission Bay, San Francisco, California Children's Hospital Colorado, Aurora, Colorado Children's National Medical Center, Washington D.C., District of Columbia Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia Lurie Children's Hospital-Chicago, Chicago, Illinois Riley Hospital for Children, Indianapolis, Indiana C S Mott Children's Hospital, Ann Arbor, Michigan University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota Washington University School of Medicine, St Louis, Missouri NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania Saint Jude Children's Research Hospital, Memphis, Tennessee Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas Seattle Children's Hospital, Seattle, Washington Key details Sponsor
Children's Oncology Group
Collaborators
Geron Corporation, National Cancer Institute (NCI)
Enrollment target
~36 participants
Primary completion
June 2026
Last updated February 2026