Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.
(77 sites) United States
Comprehensive Blood and Cancer Center, Bakersfield, California City of Hope National Medical Center, Duarte, California City of Hope Orange County Lennar Foundation Cancer Center, Duarte, California University of California San Diego Moores Cancer Center, La Jolla, California Translational Research in Oncology US Inc, Trio Central Pharmacy, Los Angeles, California University of California Los Angeles, Santa Monica, California Rocky Mountain Cancer Centers, Aurora, Colorado Hartford Hospital, Hartford, Connecticut Yale University, New Haven, Connecticut Norwalk Hospital, Norwalk, Connecticut University of Chicago, Chicago, Illinois Indiana University, Indianapolis, Indiana Norton Cancer Institute, Louisville, Kentucky Beth Israel Deaconess Medical Center, Boston, Massachusetts Dana-Farber Cancer Institute, Boston, Massachusetts Washington University, St Louis, Missouri University of Nebraska, Omaha, Nebraska Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada Memorial Sloan Kettering Cancer Center, New York, New York Duke University, Durham, North Carolina Cleveland Clinic Foundation, Cleveland, Ohio United States Oncology Regulatory Affairs Corporate Office, Nashville, Tennessee Oncology Consultants Cancer Center, Houston, Texas US Oncology Research Investigational Products Center, Irving, Texas University of Virginia Cancer Center, Charlottesville, Virginia Virginia Cancer Specialists PC, Fairfax, Virginia Fred Hutchinson Cancer Center, Seattle, Washington Northwest Medical Specialties, PLLC, Tacoma, Washington Northwest Cancer Specialists - Vancouver, Vancouver, Washington Australia
Chris OBrien Lifehouse, Camperdown, New South Wales GenesisCare -North Shore Oncology, St Leonards, New South Wales The Queen Elizabeth Hospital, Woodville South, South Australia Austin Health, Austin Hospital, Heidelberg, Victoria Peter MacCallum Cancer Centre, Melbourne, Victoria Epworth Healthcare, St Albans, Victoria Belgium
Universite Catholique de Louvain Cliniques Universitaires Saint Luc, Brussels Universitair Ziekenhuis Antwerpen, Edegem Universitair Ziekenhuis Leuven - Campus Gasthuisberg, Leuven Canada
Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta Princess Margaret Cancer Centre, Toronto, Ontario CHU de Quebec Hopital de l Enfant Jesus, Québec, Quebec China
Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, Fujian Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong Harbin Medical University Cancer Hospital, Harbin, Heilongjiang The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei The First Bethune Hospital of Jilin University, Changchun, Jilin Denmark
Herlev og Gentofte Hospital, Herlev France
Institut Bergonie, Bordeaux Centre Georges Francois Leclerc, Dijon Institut Paoli Calmettes, Marseille Gustave Roussy, Villejuif Germany
Universitaetsklinikum Essen, Essen Universitaetsklinikum Heidelberg, Heidelberg Universitaetsklinikum Wuerzburg, Würzburg Greece
Alexandra Hospital, Athens General Hospital Of Thessaloniki Papageorgiou, Thessaloniki European Interbalkan Medical Center, Thessaloniki Hong Kong
Queen Mary Hospital, The University of Hong Kong, Hong Kong Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories Italy
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milan IRCCS Istituto Clinico Humanitas, Rozzano MI Centro Ricerche Cliniche Di Verona Societa responsabilita limitata, Verona Japan
Aichi Cancer Center, Nagoya, Aichi-ken National Cancer Center Hospital East, Kashiwa-shi, Chiba Kanagawa Prefectural Hospital Organization Kanagawa Cancer Center, Yokohama, Kanagawa National Cancer Center Hospital, Chuo-ku, Tokyo Netherlands
Radboud Universitair Medisch Centrum, Nijmegen Spain
Hospital Universitario Virgen del Rocio, Seville, Andalusia Hospital Universitari Vall d Hebron, Barcelona, Catalonia Hospital General Universitario Gregorio Maranon, Madrid Taiwan
National Cheng Kung University Hospital, Tainan National Taiwan University Hospital, Taipei Taipei Veterans General Hospital, Taipei United Kingdom
Queen Elizabeth Hospital Birmingham, Birmingham Sarah Cannon Research Institute UK, London