A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

Recruiting

Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.

Trial locations(38 sites)

United States

Phoenix Children's Hospital, Phoenix, Arizona

Children's Hospital Los Angeles, Los Angeles, California

University of California, Los Angeles (UCLA), Los Angeles, California

UCSF Benioff Children's Hospital, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Children's National Hospital, Washington D.C., District of Columbia

Nicklaus Children's Hospital, Miami, Florida

Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois

University of Iowa, Iowa City, Iowa

Children's Hospital New Orleans, New Orleans, Louisiana

University of Michigan, Ann Arbor, Michigan

Children's Hospital of Michigan, Detroit, Michigan

Mayo Clinic, Rochester, Minnesota

Children's Mercy Hospital, Kansas City, Missouri

University of Nebraska Medical Center, Omaha, Nebraska

Morristown Medical Center, Morristown, New Jersey

NYP/Columbia University Medical Center, New York, New York

Children's Hospital at Montefiore, The Bronx, New York

Duke Clinical Research Institute, Durham, North Carolina

Oregon Health & Science University, Portland, Oregon

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

LeBonheur Children's Hospital, Memphis, Tennessee

Vanderbilt University Medical Center, Nashville, Tennessee

Dell Children's Hospital, Austin, Texas

UT Southwestern, Dallas, Texas

Children's Wisconsin, Milwaukee, Wisconsin

Canada

The Hospital for Sick Children (SickKids), Toronto, Ontario

Italy

Azienda Ospedaliera Universitaria Meyer IRCCS, Florence

Japan

NHO Kagoshima Medical Center, Kagoshima

University of Osaka Hospital, Osaka

Kitasato University Hospital, Sagamihara

National Cerebral and Cardiovascular Center, Suita

Juntendo University Hospital, Tokyo

Spain

Unidad de Cardiología Infantil; Hospital Universitario da Coruña, A Coruña

Hospital Sant Joan de Deu, Barcelona

United Kingdom

Alder Hey Children's Hospital, Liverpool

Evelina Children's Hospital, London

Great Ormond Street Hospital for Children, London