Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body — Stella
Phase 3 — Large-scale testing across thousands of people, comparing the new treatment against current standard treatments.
(174 sites) United States
Highlands Oncology Group - Fayetteville, Fayetteville, Arkansas Highlands Oncology Group - Rogers, Rogers, Arkansas Highlands Oncology Group, Springdale, Arkansas Tibor Rubin VA Medical Center, Long Beach, California Beebe Medical Center, Lewes, Delaware Beebe South Coastal Health Campus, Millville, Delaware Helen F Graham Cancer Center, Newark, Delaware Medical Oncology Hematology Consultants PA, Newark, Delaware Christiana Care Health System-Christiana Hospital, Newark, Delaware Beebe Health Campus, Rehoboth Beach, Delaware Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware Holy Cross Hospital, Fort Lauderdale, Florida Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho
Key details Sponsor
SWOG Cancer Research Network
Collaborators
National Cancer Institute (NCI)
Enrollment target
~528 participants
Primary completion
June 2029
Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho Idaho Urologic Institute-Meridian, Meridian, Idaho Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho Illinois CancerCare-Bloomington, Bloomington, Illinois Illinois CancerCare-Canton, Canton, Illinois Memorial Hospital of Carbondale, Carbondale, Illinois SIH Cancer Institute, Carterville, Illinois Illinois CancerCare-Carthage, Carthage, Illinois Centralia Oncology Clinic, Centralia, Illinois Northwestern University, Chicago, Illinois University of Illinois, Chicago, Illinois Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois Decatur Memorial Hospital, Decatur, Illinois Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois Illinois CancerCare-Dixon, Dixon, Illinois Crossroads Cancer Center, Effingham, Illinois Illinois CancerCare-Eureka, Eureka, Illinois Illinois CancerCare-Galesburg, Galesburg, Illinois Western Illinois Cancer Treatment Center, Galesburg, Illinois Northwestern Medicine Cancer Center Delnor, Geneva, Illinois Northwestern Medicine Glenview Outpatient Center, Glenview, Illinois Northwestern Medicine Grayslake Outpatient Center, Grayslake, Illinois Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois Illinois CancerCare-Macomb, Macomb, Illinois Cancer Care Center of O'Fallon, O'Fallon, Illinois HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois Northwestern Medicine Orland Park, Orland Park, Illinois Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois Illinois CancerCare-Pekin, Pekin, Illinois Illinois CancerCare-Peoria, Peoria, Illinois Methodist Medical Center of Illinois, Peoria, Illinois Illinois CancerCare-Peru, Peru, Illinois Valley Radiation Oncology, Peru, Illinois Illinois CancerCare-Princeton, Princeton, Illinois Southern Illinois University School of Medicine, Springfield, Illinois Springfield Clinic, Springfield, Illinois Memorial Medical Center, Springfield, Illinois Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois Illinois CancerCare - Washington, Washington, Illinois Reid Health, Richmond, Indiana Mercy Hospital, Cedar Rapids, Iowa Oncology Associates at Mercy Medical Center, Cedar Rapids, Iowa Christiana Care - Union Hospital, Elkton, Maryland Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan Trinity Health Medical Center - Brighton, Brighton, Michigan Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan Trinity Health Medical Center - Canton, Canton, Michigan Caro Cancer Center, Caro, Michigan Chelsea Hospital, Chelsea, Michigan Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan Hematology Oncology Consultants-Clarkston, Clarkston, Michigan Newland Medical Associates-Clarkston, Clarkston, Michigan Henry Ford Health Saint John Hospital, Detroit, Michigan Great Lakes Cancer Management Specialists-Doctors Park, East China Township, Michigan Genesee Cancer and Blood Disease Treatment Center, Flint, Michigan Genesee Hematology Oncology PC, Flint, Michigan Genesys Hurley Cancer Institute, Flint, Michigan Hurley Medical Center, Flint, Michigan Great Lakes Cancer Management Specialists-Van Elslander Cancer Center, Grosse Pointe Woods, Michigan Henry Ford Saint John Hospital - Academic, Grosse Pointe Woods, Michigan Henry Ford Saint John Hospital - Breast, Grosse Pointe Woods, Michigan University of Michigan Health - Sparrow Lansing, Lansing, Michigan Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan Great Lakes Cancer Management Specialists-Macomb Medical Campus, Macomb, Michigan Henry Ford Warren Hospital - Breast Macomb, Macomb, Michigan Saint Mary's Oncology/Hematology Associates of Marlette, Marlette, Michigan Hope Cancer Center, Pontiac, Michigan Michigan Healthcare Professionals Pontiac, Pontiac, Michigan Newland Medical Associates-Pontiac, Pontiac, Michigan Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan MyMichigan Medical Center Saginaw, Saginaw, Michigan Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan MyMichigan Medical Center Tawas, Tawas City, Michigan Great Lakes Cancer Management Specialists-Macomb Professional Building, Warren, Michigan Henry Ford Madison Heights Hospital - Breast, Warren, Michigan Saint John Macomb-Oakland Hospital, Warren, Michigan Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan Huron Gastroenterology PC, Ypsilanti, Michigan Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan Minnesota Oncology - Burnsville, Burnsville, Minnesota Cambridge Medical Center, Cambridge, Minnesota Mercy Hospital, Coon Rapids, Minnesota Fairview Southdale Hospital, Edina, Minnesota Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota Saint John's Hospital - Healtheast, Maplewood, Minnesota Abbott-Northwestern Hospital, Minneapolis, Minnesota Hennepin County Medical Center, Minneapolis, Minnesota Health Partners Inc, Minneapolis, Minnesota Monticello Cancer Center, Monticello, Minnesota New Ulm Medical Center, New Ulm, Minnesota Fairview Northland Medical Center, Princeton, Minnesota North Memorial Medical Health Center, Robbinsdale, Minnesota Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota Regions Hospital, Saint Paul, Minnesota United Hospital, Saint Paul, Minnesota Saint Francis Regional Medical Center, Shakopee, Minnesota Lakeview Hospital, Stillwater, Minnesota Ridgeview Medical Center, Waconia, Minnesota Rice Memorial Hospital, Willmar, Minnesota Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota Fairview Lakes Medical Center, Wyoming, Minnesota University of Mississippi Medical Center, Jackson, Mississippi Saint Francis Medical Center, Cape Girardeau, Missouri Southeast Cancer Center, Cape Girardeau, Missouri Parkland Health Center - Farmington, Farmington, Missouri Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri Missouri Baptist Medical Center, St Louis, Missouri Missouri Baptist Sullivan Hospital, Sullivan, Missouri BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri Community Hospital of Anaconda, Anaconda, Montana Billings Clinic Cancer Center, Billings, Montana Bozeman Health Deaconess Hospital, Bozeman, Montana Benefis Sletten Cancer Institute, Great Falls, Montana Great Falls Clinic, Great Falls, Montana Kalispell Regional Medical Center, Kalispell, Montana Community Medical Center, Missoula, Montana Nebraska Medicine-Bellevue, Bellevue, Nebraska Nebraska Medicine-Village Pointe, Omaha, Nebraska University of Nebraska Medical Center, Omaha, Nebraska Indu and Raj Soin Medical Center, Beavercreek, Ohio Saint Elizabeth Boardman Hospital, Boardman, Ohio Dayton Physicians LLC-Miami Valley South, Centerville, Ohio Oncology Hematology Care Inc-Kenwood, Cincinnati, Ohio Dayton Physician LLC - Englewood, Dayton, Ohio Armes Family Cancer Center, Findlay, Ohio Blanchard Valley Hospital, Findlay, Ohio Orion Cancer Care, Findlay, Ohio Dayton Physicians LLC-Atrium, Franklin, Ohio Dayton Physicians LLC-Wayne, Greenville, Ohio Wayne Hospital, Greenville, Ohio Greater Dayton Cancer Center, Kettering, Ohio Kettering Medical Center, Kettering, Ohio Dayton Physicians LLC - Troy, Troy, Ohio Saint Joseph Warren Hospital, Warren, Ohio Saint Elizabeth Youngstown Hospital, Youngstown, Ohio University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma Saint Alphonsus Cancer Care Center-Baker City, Baker City, Oregon Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania Pocono Medical Center, East Stroudsburg, Pennsylvania Lehigh Valley Hospital-Hazleton, Hazleton, Pennsylvania The West Clinic - Wolf River, Germantown, Tennessee MD Anderson in The Woodlands, Conroe, Texas Lyndon Baines Johnson General Hospital, Houston, Texas M D Anderson Cancer Center, Houston, Texas MD Anderson West Houston, Houston, Texas MD Anderson League City, League City, Texas MD Anderson in Sugar Land, Sugar Land, Texas VCU Massey Cancer Center at Stony Point, Richmond, Virginia Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia Cancer Center of Western Wisconsin, New Richmond, Wisconsin Billings Clinic-Cody, Cody, Wyoming Welch Cancer Center, Sheridan, Wyoming Last updated January 2026