Testing a new cancer treatment for advanced solid tumors

This is a first-in-human study testing a new medication called SMP-3124LP to treat adults with advanced cancers that have progressed despite standard therapy. Researchers will first determine the safest and most effective dose, then expand the study to test this medication in larger groups of patients with specific cancer types. The trial will measure how well the medication works, how the body processes it, and what side effects occur.

Many patients with advanced cancers—including ovarian cancer, triple-negative breast cancer, and others—run out of effective treatment options when their disease stops responding to standard therapies. This medication represents a new approach that researchers hope may help control these hard-to-treat cancers.