Study of Natriuretic Peptide Receptor 1 (NPR1) Antagonist in Adult Patients With Postural Orthostatic Tachycardia Syndrome (POTS) — StellaPhase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.
Trial locations(18 sites)
United States
Mercy Gilbert Medical Center, Gilbert, Arizona North County Neurology Associates, Carlsbad, California Stanford University, Palo Alto, California Southern California Heart Specialists, Pasadena, California Yale University, New Haven, Connecticut Innovative Research of West Florida, Inc., Clearwater, Florida Indiana University Health Neuroscience Center, Indianapolis, Indiana Beth Israel Deaconess Medical Center, Boston, Massachusetts Mayo Clinic, Rochester, Minnesota Saint Luke's MidAmerica Heart Institute, Kansas City, Missouri New York University Langone, New York, New York Columbia University, New York, New York University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma Vanderbilt University Medical Center, Nashville, Tennessee University of Texas Southwestern, Dallas, Texas University of Utah, Salt Lake City, Utah Canada
University of Calgary, Calgary, Alberta University of Alberta Hospital, Edmonton, Alberta Last updated February 2026