A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

Recruiting

Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.

Trial locations(26 sites)

United States

UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine, California

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida

UM Sylvester Comprehensive Cancer Center at Coral Springs, Coral Springs, Florida

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida

UM Sylvester Comprehensive Cancer Center at Doral, Doral, Florida

UM Sylvester Comprehensive Cancer Center at Hollywood, Hollywood, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

UM Sylvester Comprehensive Cancer Center at Kendall, Miami, Florida

University of Miami Sylvester Comprehensive Cancer Center at Sole Mia, North Miami, Florida

UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida

Moffitt Cancer Center, Tampa, Florida

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois

University of Chicago Medicine-Orland Park, Orland Park, Illinois

UChicago Medicine Northwest Indiana, Crown Point, Indiana

University of Kansas Clinical Research Center, Fairway, Kansas

University of Kansas Cancer Center, Kansas City, Kansas

University of Kansas Hospital-Indian Creek Campus, Overland Park, Kansas

University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas

NYP/Weill Cornell Medical Center, New York, New York

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Oregon Health and Science University, Portland, Oregon

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

VCU Massey Comprehensive Cancer Center, Richmond, Virginia