Plain-English translation of NCT06810934 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing two experimental COVID-19 booster vaccines called CoTend-s3BXBB and CoTend-BXBB in healthy adults. One vaccine includes an extra component designed to boost your immune response; the other does not. Researchers want to find out if this new treatment is safe and whether the extra component helps your body fight COVID-19 better and longer.
Even though standard COVID-19 vaccines work well, scientists are exploring whether this medication can create stronger and longer-lasting protection against the virus, especially as immunity from earlier vaccines fades over time.
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You will receive a single injection of either one of the two experimental vaccines or a placebo (a dummy shot with no active ingredient). The researchers will monitor you for side effects and ask you to report how you feel. You will provide blood samples, nasal swabs, and saliva samples at different time points so researchers can measure how your immune system responds to the vaccine.
AI-generated summary from trial data · Aug 26, 2026 · Not medical advice
United States