A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab — Stella
Phase 3 — Large-scale testing across thousands of people, comparing the new treatment against current standard treatments.
(270 sites) United States
Gastro Health Research - St. Vincent'S East /ID# 275089, Birmingham, Alabama Digestive Health Specialists /ID# 274785, Dothan, Alabama East View Medical Research /ID# 276222, Mobile, Alabama Arizona Health Research /ID# 274366, Chandler, Arizona UC San Diego Health System /ID# 273538, La Jolla, California Gastro Care Institute /ID# 274873, Lancaster, California UCLA Health - Digestive Health & Nutrition Clinic /ID# 274827, Los Angeles, California Hoag Memorial Hospital Presbyterian /ID# 274364, Newport Beach, California California Medical Research Associates /ID# 274787, Northridge, California uc davis medical center - patient support services building /ID# 274251, Sacramento, California Clinical Applications Laboratories - San Diego - 3rd Avenue /ID# 273527, San Diego, California Danbury Hospital, Western Connecticut Health Network /ID# 275277, Danbury, Connecticut Novum Research /ID# 273587, Clermont, Florida Hillcrest Medical Research /ID# 273593, DeLand, Florida Florida Research Institute /ID# 275196, Lakewood Rch, Florida Sanchez Clinical Research /ID# 273727, Miami, Florida Medical Professional Clinical Research /ID# 275208, Miami, Florida Sarkis Clinical Trials - Ocala /ID# 273595, Ocala, Florida Endoscopic Research, Inc. /ID# 273548, Orlando, Florida Digestive And Liver Center Of Florida - Orlando /ID# 276432, Orlando, Florida Emory University School Of Medicine - Atlanta /ID# 273522, Atlanta, Georgia Gi Alliance - Glenview /ID# 274270, Glenview, Illinois Illinois Gastroenterology Group /ID# 274280, Gurnee, Illinois Southwest Gastroenterology - Oak Lawn /ID# 273596, Oak Lawn, Illinois OSF St. Francis Medical Center /ID# 274391, Peoria, Illinois Springfield Clinic Main Campus /ID# 273547, Springfield, Illinois Gastroenterology Health Partners /ID# 276434, New Albany, Indiana Iowa Digestive Disease Center - Clive /ID# 274558, Clive, Iowa Cotton O'Neil Digestive Health Center /ID# 274394, Topeka, Kansas Gastroenterology Health Partners, PLLC /ID# 276441, Louisville, Kentucky Tandem Clinical Research - Houma /ID# 274562, Houma, Louisiana Metropolitan Gastroenterology Associates - Metairie /ID# 274282, Metairie, Louisiana Pinnacle Gastroenterology /ID# 274991, Shreveport, Louisiana Louisiana Research Center, LLC /ID# 276443, Shreveport, Louisiana Velocity Clinical Research, Rockville /ID# 273599, Rockville, Maryland Brigham & Womens Hospital /ID# 275266, Boston, Massachusetts Lucida Clinical Trials /ID# 275235, New Bedford, Massachusetts Huron Gastroenterology /ID# 274998, Ann Arbor, Michigan Mayo Clinic-Rochester /ID# 273606, Rochester, Minnesota Gi Associates - Gia And Endoscopy Center - Flowood /ID# 274285, Flowood, Mississippi Delta Gastroenterology & Endoscopy Center /ID# 275005, Southaven, Mississippi Columbia University Medical Center /ID# 273518, New York, New York New York Gastroenterology Associates - Upper East Side /ID# 273520, New York, New York Gastroenterology Group of Rochester /ID# 274283, Rochester, New York Digestive Health Partners - Biltmore Office /ID# 273594, Asheville, North Carolina Atrium Health - Morehead /ID# 274245, Charlotte, North Carolina Charlotte Gastroenterology And Hepatology - Randolph Road /ID# 274553, Charlotte, North Carolina Carolina Digestive Diseases And Endoscopy Center /ID# 274256, Greenville, North Carolina Digestive Disease Consultants - Brunswick /ID# 276445, Brunswick, Ohio Gastro Health /ID# 275082, Cincinnati, Ohio University Of Cincinnati Medical Center /ID# 273524, Cincinnati, Ohio The Ohio State University - Wexner Medical Center /ID# 274743, Columbus, Ohio Dayton Gastroenterology, Inc /ID# 273528, Dayton, Ohio Digestive Disease Associates, LTD - Wyomissing /ID# 273603, Wyomissing, Pennsylvania Gastroenterology Associates of Orangeburg /ID# 274559, Orangeburg, South Carolina Gastro One - Walnut Run Road /ID# 273551, Cordova, Tennessee Skyline Gastroenterology of West Tennessee /ID# 276461, Jackson, Tennessee GI associates of Northeast Tennessee /ID# 273758, Johnson City, Tennessee Tri-Cities Gastroenterology /ID# 275067, Kingsport, Tennessee Gastrointestinal Associates - Knoxville - Dowell Springs Boulevard /ID# 276447, Knoxville, Tennessee Quality Medical Research /ID# 273733, Nashville, Tennessee Amel Med /ID# 276439, Georgetown, Texas Digestive & Liver Disease Consultants /ID# 276454, Houston, Texas Katy Integrative Gastroenterology /ID# 274645, Katy, Texas Caprock Gastro Research - Lubbock - 80th Street /ID# 273778, Lubbock, Texas GI Alliance: Mansfield /ID# 274272, Mansfield, Texas Linq Research /ID# 274917, Pearland, Texas Tyler Research Institute, LLC /ID# 273585, Tyler, Texas Care Access - Ogden /ID# 274361, Ogden, Utah Gastroenterology Associates Of Tidewater - Chesapeake /ID# 276440, Chesapeake, Virginia Emeritas Research Group /ID# 276457, Lansdowne Town Center, Virginia Gi Alliance - Bellevue /ID# 274264, Bellevue, Washington Virginia Mason Hospital & Medical Center /ID# 274810, Seattle, Washington Washington Gastroenterology - Tacoma /ID# 274551, Tacoma, Washington Austria
Medizinische Universitaet Graz /ID# 274428, Graz, Styria Ordensklinikum Linz GmbH Barmherzige Schwestern /ID# 274318, Linz, Upper Austria Klinikum Wels-Grieskirchen GmbH /ID# 274172, Wels, Upper Austria Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 273611, Salzburg Medizinische Universitaet Wien /ID# 273612, Vienna Bulgaria
Hospital Tsaritsa Yoanna /ID# 274723, Sofiya, Sofia Umhat Sveti Ivan Rilsky /ID# 274794, Sofiya, Sofia Acibadem City Clinic UMHAT Mladost /ID# 274804, Sofiya, Sofia Umbal Kaspela /ID# 274721, Plovdiv MHAT Knyaginya Klementina /ID# 274722, Sofia Mhat Doverie /ID# 274798, Sofia Canada
University Of Calgary - Health Sciences Centre /ID# 274237, Calgary, Alberta Gastroenterology and Internal Medicine Research Institute /ID# 274239, Edmonton, Alberta South Edmonton Gastroenterology /ID# 274184, Edmonton, Alberta Barrie GI Associates /ID# 275211, Barrie, Ontario Brampton Gastroenterology Inc /Id# 276187, Brampton, Ontario GNRR Digestive Clinics and Research Center Inc. /ID# 275820, Brampton, Ontario The Oakville Endoscopy Centre /ID# 275213, Oakville, Ontario Toronto Immune & Digestive Health Institute /ID# 274259, Toronto, Ontario Montreal General Hospital /ID# 275201, Montreal, Quebec Diex Recherche Quebec Inc. /ID# 274268, Québec China
The First Affiliated Hospital Of Anhui Medical University /ID# 274786, Hefei, Anhui Peking Union Medical College Hospital (East) - Dongdan Campus /ID# 274886, Beijing, Beijing Municipality Chongqing General Hospital /ID# 274564, Chongqing, Chongqing Municipality The First Affiliated Hospital, Sun-Yat Sen University /ID# 274823, Guangzhou, Guangdong The Sixth Affiliated Hospital of Sun Yat-sen University /ID# 274843, Guangzhou, Guangdong The Second Hospital Of Hebei Medical University /ID# 274822, Shijiazhuang, Hebei The Second Affiliated Hospital Of Zhengzhou University /ID# 274569, Zhengzhou, Henan Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 274563, Wuhan, Hubei Renmin Hospital of Wuhan University /ID# 274616, Wuhan, Hubei The Second Xiangya Hospital Of Central South University /ID# 274712, Changsha, Hunan Nanjing Drum Tower Hospital /ID# 274710, Nanjing, Jiangsu Croatia
Klinicki Bolnicki Centar Zagreb /ID# 273316, Grad Zagreb, City of Zagreb Poliklinika Solmed /ID# 273323, Zagreb, City of Zagreb Poliklinika Borzan d.o.o. /ID# 273324, Osijek, County of Osijek-Baranja Specialty Hospital Medico /ID# 273334, Rijeka, Primorje-Gorski Kotar County Klinicki Bolnicki Centar (KBC) Split /ID# 273327, Split, Split-Dalmatia County Czechia
Hepato-Gastroenterologie HK /ID# 276654, Hradec Králové, Hradec Kralove Nemocnice Ceske Budejovice /ID# 276530, České Budějovice Estonia
Parnu Hospital /ID# 273584, Pärnu East Tallinn Central Hospital /ID# 273723, Tallinn West Tallinn Central Hospital /ID# 273722, Tallinn Finland
Kuopion Yliopistollinen Sairaala /ID# 274856, Kuopio, Northern Savonia Turku University Hospital /ID# 274312, Turku, Southwest Finland France
Chu de Nice-Hopital Larchet Ii /Id# 278595, Nice, Alpes-Maritimes CHU de Montpellier - Hopital Saint Eloi /ID# 278594, Montpellier, Herault Hopitaux Universitaires Henri Mondor - Hopital Henri Mondor /ID# 278633, Créteil, Paris Centre Hospitalier Universitaire de Saint Etienne - Hopital Nord /ID# 278587, St-Priest-en-Jarez, Pays de la Loire Region Hopital Saint Antoine /ID# 278593, Paris Germany
Universitaetsklinikum Freiburg /ID# 274763, Freiburg im Breisgau, Baden-Wurttemberg Universitaetsklinikum Ulm /ID# 273411, Ulm, Baden-Wurttemberg Medizinisches Versorgungszentrum Dachau /ID# 273458, Dachau, Bavaria Universitaetsklinikum Erlangen /ID# 273504, Erlangen, Bavaria Markus Krankenhaus /ID# 273436, Frankfurt am Main, Hesse Universitaetsklinikum Frankfurt /ID# 273462, Frankfurt am Main, Hesse Universitaetsmedizin Essen /ID# 273505, Essen, North Rhine-Westphalia Gastroenterologische Gemeinschaftspraxis Minden /ID# 273447, Minden, North Rhine-Westphalia Magen-Darm-Zentrum-Remscheid /ID# 273435, Remscheid, North Rhine-Westphalia Universitaetsklinikum Carl Gustav Carus Dresden /ID# 273448, Dresden, Saxony Eugastro /ID# 273573, Leipzig, Saxony Studiengesellschaft BSF Unternehmergesellschaft /ID# 273457, Halle, Saxony-Anhalt
Hungary
Debreceni Egyetem-Klinikai Kozpont /ID# 275083, Debrecen, Hajdú-Bihar Clinfan /ID# 274904, Szekszárd, Tolna County Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz /ID# 275077, Szombathely, Vas County Obudai Egeszsegugyi Centrum /ID# 274919, Budapest Eszak-Pesti Centrumkorhaz - Honvedkorhaz - Podmaniczky Utca /ID# 275722, Budapest Semmelweis Egyetem /ID# 274872, Budapest Semmelweis Egyetem /ID# 274883, Budapest Pannónia Magánorvosi Centrum /ID# 275723, Budapest Szegedi Tudomanyegyetem /ID# 275185, Szeged Ireland
Portiuncula University Hospital /ID# 273782, Ballinasloe, Galway Our Lady of Lourdes Hospital - Drogheda /ID# 273783, Drogheda, Louth Midland Regional Hospital Mullingar /ID# 273784, Mullingar, Westmeath St. Vincent's University Hospital /ID# 274617, Dublin Beaumont Hospital /ID# 273787, Dublin Connolly Hospital /ID# 274173, Dublin Israel
Yitzhak Shamir Medical Center /ID# 275525, Ẕerifin, Central District Assuta Ashdod Medical Center /ID# 274686, Ashdod, Southern District Soroka Medical Center /ID# 273350, Beersheba, Southern District The Chaim Sheba Medical Center /ID# 273348, Ramat Gan, Tel Aviv Tel Aviv Sourasky Medical Center /ID# 273351, Tel Aviv, Tel Aviv Rambam Health Care Campus- Haifa /ID# 273347, Haifa Rabin Medical Center. /ID# 280537, Petah Tikva Italy
Azienda Ospedaliero Universitaria di Cagliari - P.O. Duilio Casula /ID# 274683, Monserrato, Cagliari IRCCS Istituto Clinico Humanitas /ID# 274518, Rozzano, Lombardy IRCCS Ospedale San Raffaele /ID# 274516, Milan, Milano Azienda Ospedaliera Universitaria Federico II /ID# 274828, Naples, Napoli Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Universita Cattolica /ID# 274685, Rome, Roma IRCCS AOU di Bologna Policlinico Sant Orsola Malpighi /ID# 274520, Bologna Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico /ID# 274517, Milan Azienda Ospedale-Universita Padova /ID# 274519, Padova Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone /ID# 274824, Palermo Azienda Ospedaliero Universitaria Pisana /ID# 274829, Pisa Latvia
Liepaja Regional Hospital /ID# 275164, Liepāja Pauls Stradins Clinical University Hospital /ID# 273586, Riga Digestive Diseases Center GASTRO /ID# 273589, Riga Lithuania
Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 273590, Kaunas Panevezys Republican Hospital /ID# 273592, Panevezys Vilnius University Hospital Santaros Klinikos /ID# 273591, Vilnius Inlita - Lazdynai CTC /ID# 273725, Vilnius Netherlands
Radboudumc /ID# 274797, Nijmegen, Gelderland Elisabeth TweeSteden Ziekenhuis /ID# 274940, Tilburg, North Brabant OLVG - Locatie Oost /ID# 274809, Amsterdam, North Holland Amsterdam UMC, locatie AMC /ID# 274939, Amsterdam, North Holland Albert Schweitzer Ziekenhuis, locatie Dordwijk /ID# 274936, Dordrecht, South Holland Erasmus Medisch Centrum /ID# 274795, Rotterdam, South Holland Franciscus Gasthuis & Vlietland, Locatie Gasthuis /ID# 274806, Rotterdam, South Holland Poland
RIVERMED Sp. z o. o. /ID# 274420, Poznan, Greater Poland Voivodeship Osrodek Badan Klinicznych Clinsante /ID# 274190, Bydgoszcz, Kuyavian-Pomeranian Voivodeship PROMED P. Lach, R. Glowacki S.j /ID# 274392, Krakow, Lesser Poland Voivodeship EMC Instytut Medyczny S.A /ID# 275113, Wroclaw, Lower Silesian Voivodeship Centrum Zdrowia Mdm /ID# 274192, Warsaw, Masovian Voivodeship Panstwowy Instytut Medyczny MSWiA /ID# 274538, Warsaw, Masovian Voivodeship WSD MEDI Clinical Sp. z o.o. /ID# 274194, Warsaw, Masovian Voivodeship Centrum Medyczne Lukamed Sp. z o.o /ID# 274193, Chojnice, Pomeranian Voivodeship Novamed Robert Koteras /ID# 274547, Bytom, Silesian Voivodeship Twoja Przychodnia Szczecińskie Centrum Medyczne /ID# 274187, Szczecin, West Pomeranian Voivodeship Puerto Rico
ISIS Clinical Research Center /ID# 274859, Guaynabo CMRC Headlands LLC /ID# 274832, San Juan Fdi Clinical Research /ID# 275337, San Juan Romania
Memorial Healthcare International S.R.L. /Id# 276040, Bucharest, Bucharest Spitalul Clinic Colentina /ID# 275892, Bucharest, Bucharest Fundeni Clinical Institute /ID# 275893, Bucharest, Bucharest Clinica Gastro Med SRL /ID# 275891, Cluj-Napoca, Cluj OncoHelp Association /ID# 275889, Timișoara, Timiș County Monza-Ares S.R.L. /Id# 276048, Bucharest Saudi Arabia
King Abdulaziz Medical City- National Guard Hospital /ID# 274817, Riyadh, Riyadh Region King Saud University /ID# 274818, Riyadh, Riyadh Region King Faisal Specialist Hospital and Research Center /ID# 274819, Riyadh, Riyadh Region King Fahad Specialist Hospital /ID# 274820, Dammam Slovakia
Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 274740, Banská Bystrica, Banská Bystrica Region KM Management, spol. s.r.o. /ID# 274733, Nitra, Nitra Region ENDOMED s.r.o /ID# 274734, Košice Slovenia
Splosna Bolnisnica Nova Gorica /ID# 275635, Šempeter Pri Gorici, Urban Municipality of Nova Gorica General Hospital Celje /ID# 275127, Celje University Medical Centre Ljubljana /ID# 273636, Ljubljana South Korea
Inje University Haeundae Paik Hospital /ID# 274435, Busan, Busan Gwang Yeogsi Kyungpook National University Hospital /ID# 274439, Daegu, Daegu Gwang Yeogsi The Catholic University of Korea, Daejeon St. Mary's Hospital /ID# 274429, Daejeon, Daejeon Gwang Yeogsi Seoul National University Bundang Hospital /ID# 274441, Seongnam-si, Gyeonggido The Catholic University Of Korea St. Vincent's Hospital /ID# 274433, Suwon, Gyeonggido Chosun University Hospital /ID# 276672, Gwangju, Jeonranamdo Seoul National University Hospital /ID# 274438, Seoul, Seoul Teugbyeolsi Yonsei University Health System Severance Hospital /ID# 274431, Seoul, Seoul Teugbyeolsi Gangnam Severance Hospital /ID# 274436, Seoul, Seoul Teugbyeolsi Samsung Medical Center /ID# 274440, Seoul, Seoul Teugbyeolsi Spain
Complejo Hospitalario Universitario de Santiago (CHUS) /ID# 274266, Santiago de Compostela, A Coruna Hospital General De Granollers /ID# 274384, Granollers, Barcelona Sant Joan de Deu de Manresa /ID# 274288, Manresa, Barcelona Hospital Universitario de Gran Canaria Doctor Negrín /ID# 274277, Las Palmas de Gran Canaria, Las Palmas Hospital Universitario Fundación Alcorcón /ID# 274309, Alcorcón, Madrid Hospital Universitario Puerta De Hierro /ID# 274271, Majadahonda, Madrid Hospital de Cabueñes /ID# 274254, Gijón, Principality of Asturias Hospital Universitario Virgen Macarena /ID# 274258, Seville, Sevilla Hospital Clinic de Barcelona /ID# 274262, Barcelona Complejo Hospitalario Universitario de Pontevedra /ID# 274269, Pontevedra Consorci Hospital General Universitario de Valencia /ID# 274275, Valencia Hospital Universitario Doctor Peset /ID# 274385, Valencia Sweden
Danderyds Sjukhus - Danderyd /ID# 274401, Danderyd, Stockholm County Karolinska University Hospital Solna /ID# 274379, Solna, Stockholm County Alingsås Lasarett /ID# 274399, Alingsås, Västra Götaland County Universitetssjukhuset Örebro /ID# 274386, Örebro, Örebro County Linkoping University Hospital /ID# 274932, Linköping, Östergötland County Switzerland
Luzern Kantonsspital /ID# 275415, Lucerne, Canton of Lucerne Kantonsspital St.Gallen /ID# 273382, Sankt Gallen, Canton of St. Gallen Inselspital, Universitaetsspital Bern /ID# 273364, Bern Taiwan
China Medical University Hospital /ID# 273641, Taichung National Taiwan University Hospital /ID# 273632, Taipei Mackay Memorial Hospital /ID# 273643, Taipei Taipei Veterans General Hospital /ID# 274717, Taipei Linkou Chang Gung Memorial Hospital /ID# 273640, Taoyuan United Arab Emirates
Burjeel Medical City /ID# 274749, Abu Dhabi Sheikh Shakhbout Medical City /ID# 274643, Abu Dhabi Sheikh Khalifa Medical City /ID# 274777, Abu Dhabi United Kingdom
Barts Health NHS Trust - The Royal London Hospital /ID# 274959, London, Greater London King'S College Hospital /ID# 275223, London, Greater London Velocity North London /ID# 275581, North Finchley, Greater London Queen Elizabeth University Hospital - NHS Greater Glasgow and Clyde /ID# 274758, Glasgow, Lanarkshire Fairfield General Hospital /ID# 274947, Manchester, Lancashire The John Radcliffe Hospital /ID# 274757, Oxford, Oxfordshire Queen Elizabeth Hospital Birmingham /ID# 275287, Birmingham Stepping Hill Hospital-Stockport NHS foundation trust /ID# 275838, Stockport Key details Enrollment target
~530 participants
Primary completion
September 2028
Age range
18 Years – 80 Years
Last updated March 2026
Interested in joining? The First Affiliated Hospital of Nanchang University /ID# 274801, Nanchang, Jiangxi
The First Hospital of Jilin University /ID# 274784, Changchun, Jilin Renji Hospital, Shanghai Jiaotong University School of Medicine /ID# 275658, Shanghai, Shanghai Municipality West China Hospital of Sichuan University /ID# 275478, Chengdu, Sichuan The Second Affiliated Hospital of Zhejiang University School of Medicine /ID# 274849, Hangzhou, Zhejiang Sir Run Run Shaw Hospital of Zhejiang University School of Medicine /ID# 274689, Hangzhou, Zhejiang Praxisgemeinschaft Jerichow Schulze /ID# 273433, Jerichow, Saxony-Anhalt
Universitaetsklinikum Schleswig-Holstein - Campus Kiel /ID# 273463, Kiel, Schleswig-Holstein Praxis fuer Gastroenterologie /ID# 274546, Lübeck, Schleswig-Holstein Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 274545, Berlin Drk Kliniken Berlin - Köpenick /ID# 273514, Berlin Krankenhaus Waldfriede /ID# 273708, Berlin GSGH Gastroenterologische Studiengesellschaft Herne GbR /ID# 273459, Herne Universitaetsklinikum Regensburg /ID# 273519, Regensburg