Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer — Stella
Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.
(65 sites) United States
UC San Diego Moores Cancer Center, La Jolla, California UCHealth University of Colorado Hospital, Aurora, Colorado Lurie Children's Hospital-Chicago, Chicago, Illinois Northwestern University, Chicago, Illinois Carle at The Riverfront, Danville, Illinois Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois Carle Physician Group-Effingham, Effingham, Illinois Northwestern Medicine Cancer Center Delnor, Geneva, Illinois Northwestern Medicine Glenview Outpatient Center, Glenview, Illinois Northwestern Medicine Grayslake Outpatient Center, Grayslake, Illinois Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois Carle BroMenn Medical Center, Normal, Illinois
Key details Sponsor
National Cancer Institute (NCI)
Enrollment target
~48 participants
Primary completion
June 2029
Age range
12 Years and older
Last updated April 2026
Interested in joining? Carle Cancer Institute Normal, Normal, Illinois
Northwestern Medicine Oak Brook, Oak Brook, Illinois Northwestern Medicine Orland Park, Orland Park, Illinois Memorial Hospital East, Shiloh, Illinois Carle Cancer Center, Urbana, Illinois Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa Saint Anthony Regional Hospital, Carroll, Iowa UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa Iowa Methodist Medical Center, Des Moines, Iowa UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa Broadlawns Medical Center, Des Moines, Iowa Mercy Medical Center - Des Moines, Des Moines, Iowa UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa UI Healthcare Mission Cancer and Blood - Fort Dodge, Fort Dodge, Iowa UI Health Care Mission Cancer and Blood - Waukee Clinic, Waukee, Iowa Dana-Farber Cancer Institute, Boston, Massachusetts University of Michigan Rogel Cancer Center, Ann Arbor, Michigan Siteman Cancer Center at Saint Peters Hospital, City of Saint Peters, Missouri Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri CoxHealth South Hospital, Springfield, Missouri Washington University School of Medicine, St Louis, Missouri Siteman Cancer Center-South County, St Louis, Missouri Siteman Cancer Center at Christian Hospital, St Louis, Missouri Nebraska Medicine-Bellevue, Bellevue, Nebraska Nebraska Medicine-Village Pointe, Omaha, Nebraska University of Nebraska Medical Center, Omaha, Nebraska Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey Memorial Sloan Kettering Monmouth, Middletown, New Jersey Memorial Sloan Kettering Bergen, Montvale, New Jersey Memorial Sloan Kettering Commack, Commack, New York Memorial Sloan Kettering Westchester, Harrison, New York Memorial Sloan Kettering Cancer Center, New York, New York Memorial Sloan Kettering Nassau, Uniondale, New York Duke Cancer Center Cary, Cary, North Carolina Duke University Medical Center, Durham, North Carolina Duke Cancer Center Raleigh, Raleigh, North Carolina Ohio State University Comprehensive Cancer Center, Columbus, Ohio Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina Prisma Health Richland Hospital, Columbia, South Carolina Prisma Health Cancer Institute - Easley, Easley, South Carolina BI-LO Charities Children's Cancer Center, Greenville, South Carolina Prisma Health Cancer Institute - Butternut, Greenville, South Carolina Prisma Health Cancer Institute - Faris, Greenville, South Carolina Prisma Health Cancer Institute - Eastside, Greenville, South Carolina Prisma Health Cancer Institute - Greer, Greer, South Carolina Prisma Health Cancer Institute - Seneca, Seneca, South Carolina Saint Jude Children's Research Hospital, Memphis, Tennessee University of Texas Health Science Center at San Antonio, San Antonio, Texas VCU Massey Cancer Center at Stony Point, Richmond, Virginia VCU Massey Comprehensive Cancer Center, Richmond, Virginia