A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE) — Stella

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A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE) — Stella

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Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.

Trial locations(1 site)

United States

The University of Texas M. D. Anderson Cancer Center, Houston, Texas

Key details

Phase

Safety & dosing

Sponsor

M.D. Anderson Cancer Center

Collaborators

Exelixis

Enrollment target

~70 participants

Started

December 2025

Primary completion

October 2029

Age range

18 Years and older

Last updated February 2026

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