Plain-English translation of NCT07195149 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
After heart bypass surgery, blood clots can form in the new grafts and block blood flow. This trial compares three different approaches using blood thinners: prasugrel combined with low-dose aspirin, low-dose aspirin alone, or high-dose aspirin alone. The study will track which approach best prevents graft failure over one year.
Doctors want to find the safest and most effective blood thinner strategy after bypass surgery — one that prevents dangerous clots without causing too much bleeding. This medication combination hasn't been fully tested in this specific surgery setting yet.
You likely qualify if…
You likely don't qualify if…
You will have heart bypass surgery as planned. After surgery, you'll be randomly assigned to take one of three blood thinner regimens for three months, then low-dose aspirin alone for the remaining nine months. You'll visit the hospital or clinic for check-ups and heart imaging tests to monitor whether your grafts stay open. The study lasts 12 months total from your surgery date.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
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