Testing a New Diabetes Pill at Different Dose Levels

Plain-English translation of NCT07340320 on ClinicalTrials.gov ↗ · Source last updated May 2026 · Translation generated June 2026 · How we translate trials

Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.

What is this trial?

This study is testing a new medication called to see if it can help control blood sugar in adults with type 2 diabetes who aren't reaching their goals on metformin alone (with or without another diabetes medicine). The medication will be tested at six different dose levels, and researchers will compare how well it works and how safe it is compared to a placebo pill.

Many people with type 2 diabetes struggle to reach healthy blood sugar levels even when taking standard treatments. This medication is being developed to offer an additional option for those who need better blood sugar control.

Do you qualify?

You likely qualify if…

you are between 18 and 75 years old
you have been diagnosed with type 2 diabetes for at least 6 months
your blood sugar control (HbA1c) is between 7.0% and 10.5%, meaning it's not quite at goal
you have been taking a stable dose of metformin (at least 1000 mg per day) for at least 3 months, with or without another diabetes medication
your weight has been stable for the past 3 months
you are willing to use effective birth control throughout the study if you can become pregnant

You likely don't qualify if…

you have type 1 diabetes or a history of diabetic ketoacidosis
you have had a heart attack, stroke, or serious heart condition in the past 6 months
you are currently taking insulin or have taken it in the past 12 months
you have had more than one episode of severe low blood sugar
you have a history of pancreatitis, gallbladder disease, or certain thyroid conditions (including family history of medullary thyroid cancer)

What participation looks like

You will be randomly assigned to receive either the new medication at one of five different doses or a placebo pill. You'll take your assigned treatment for 24 weeks, during which you'll have regular visits to the study center for blood tests and check-ups. After the 24-week treatment period ends, you'll have a 2-week follow-up visit to make sure everything is going well.

AI-generated summary from trial data · Jun 7, 2026 · Not medical advice

Testing a New Diabetes Pill at Different Dose Levels

What is this trial?

Do you qualify?

What participation looks like

Trial locations