Plain-English translation of NCT00001853 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand why Black women have high heart disease risk even when they don't have the same weight or blood fat problems that put other women at risk. This study will measure body fat, blood sugar, and heart health in 2,000 Black adults to figure out which factors matter most for preventing heart disease in Black men and women.
Past research on mostly white women showed that obesity and high blood fat levels increase heart disease risk, but studies of Black women didn't find the same pattern—yet Black women still have very high rates of heart disease. Doctors need to understand these differences so they can better prevent and treat heart disease in Black communities.
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You will visit the Clinical Center twice as an outpatient. During these visits, researchers will measure your body fat, do an electrocardiogram (a quick heart rhythm test), take blood samples to check your glucose and fat levels, and ask about your health history. The whole process helps doctors understand how obesity and blood sugar affect heart disease risk differently in Black men versus Black women.
AI-generated summary from trial data · Sep 3, 2026 · Not medical advice
United States
Enrollment target
~2,000 participants
Started
October 1998
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in September 2026.
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Central contact
Christopher W DuBose, C.R.N.P.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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