New treatments and completed trials across every condition — what was tested, what was found, and what it means for patients.
Condition guides
Knee osteoarthritis affects more than 14 million adults in the US, making it one of the most common causes of chronic pain and disability.
Read the guide →Ischemic stroke happens when a blood clot blocks flow to part of the brain.
Read the guide →Fallopian tube cancer is rare, accounting for about 1% of gynecologic cancers.
Read the guide →Acute coronary syndrome is the umbrella term for heart attacks and unstable angina — when a coronary artery suddenly narrows or closes.
Read the guide →Cardiovascular diseases include heart attack, stroke, heart failure, and conditions like atrial fibrillation.
Read the guide →Myopia, or nearsightedness, affects nearly half of young adults in some countries and is becoming more common worldwide.
Read the guide →Researchers tested delgocitinib cream in 98 adolescents with moderate to severe hand eczema. After 16 weeks, 64% of teens using the cream had clear or almost clear skin, compared to 29% using a placebo cream. The treatment was well tolerated with no serious side effects.
What this means for patients
Delgocitinib cream is FDA-approved for adults with moderate to severe hand eczema. This study shows it works well in teens too, but it is not yet approved for adolescents. If your teen has severe hand eczema, ask your dermatologist whether delgocitinib or similar treatments might be right for them.
Researchers tested tavapadon, a once-daily pill, in 304 people with early Parkinson's disease. After 26 weeks, those taking tavapadon had significantly better movement and daily function scores compared to those on a sugar pill, with side effects mainly including nausea, headache, and dizziness.
Read →Researchers tested an 8-week online program combining talk therapy and gentle exercise for teens with ongoing sickle cell pain. Over 4 in 5 teens reported less pain after completing the program, and the improvement lasted at least 3 months.
Read →Kids who got at least 13 of the program's 21 steps — things like earlier eating, less pain medicine, and faster movement after surgery — went home more than a day sooner and had half as many complications. The study tracked 597 children ages 10 to 18, most with inflammatory bowel disease, across 18 hospitals.
Read →A large trial in India gave 3,000 people who inject drugs a 12-week hepatitis C cure along with varying levels of help taking it — from check-ins to observed dosing. Even with the most intensive support, only about half of high-risk participants cleared the virus. The results show that free pills and reminders aren't enough — people who inject drugs need different or more powerful help to beat hepatitis C.
Read →Researchers tested a targeted combination therapy called venetoclax-obinutuzumab against traditional chemotherapy in people newly diagnosed with chronic lymphocytic leukemia. More patients on the targeted therapy had no detectable cancer in their blood after treatment.
Read →In 239 people with severe depression, magnetic seizure therapy worked as well as electroconvulsive therapy (ECT) at stopping depression. About 23% of those who got magnetic therapy saw their depression go away, compared to 28% with ECT. The big difference: only 3% of magnetic therapy patients had memory problems, versus 17% with ECT.
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