Plain-English translation of NCT00081523 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study that invites people with sickle cell disease to participate in building a large medical resource. Researchers will collect blood samples and other biological materials from you, along with information about your medical history and current health. By studying these samples and records over time, scientists hope to better understand what causes sickle cell disease complications, especially painful crises, so they can develop better treatments.
Right now, doctors don't fully understand why some people with sickle cell disease experience more severe pain crises and complications than others. This study exists to fill that gap by collecting samples and health information from thousands of patients, which will help researchers identify the underlying causes of the disease and work toward better prevention and treatment strategies.
You likely qualify if…
You likely don't qualify if…
You will visit one of the participating clinics where you'll have a medical history taken, a physical exam, and routine blood tests to check your health and disease activity. You may also have blood or tissue samples collected and stored for future research. Your medical records and test results will be kept for researchers to study, and you may be asked to participate in other related sickle cell research studies if you're interested. The study team will work with your regular doctor to make sure any care you receive follows standard medical practice.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Enrollment target
~3,500 participants
Started
April 2004
Age range
2 Years – 90 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Nancy A Asomaning
National Heart, Lung, and Blood Institute (NHLBI)
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.