Plain-English translation of NCT00081523 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study that helps scientists learn more about sickle cell disease by collecting blood samples and medical information from people who have the condition. Researchers will store these samples and use them to study what causes sickle cell pain crises and other complications. This knowledge could eventually help doctors develop better treatments and ways to prevent these painful episodes.
Sickle cell disease causes unpredictable pain crises and many serious complications, but scientists still don't fully understand what triggers these events or why they vary so much from person to person. By studying samples and medical records from many patients, researchers hope to uncover the underlying causes of the disease so they can find better ways to treat and prevent these complications.
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You will have a medical history and physical examination, and routine blood tests will be taken to check your diagnosis and how your disease is doing. Your blood samples will be stored in a special repository for future research. You may also be invited to participate in other research studies. Apart from these activities, any medical care you receive will follow standard treatment practices and will be discussed with your regular doctor.
AI-generated summary from trial data · Jul 20, 2026 · Not medical advice
United States
Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Enrollment target
~3,500 participants
Started
April 2004
Age range
2 Years – 90 Years
Last updated on clinicaltrials.gov in July 2026.
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Central contact
Nancy A Asomaning
National Heart, Lung, and Blood Institute (NHLBI)
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.