Plain-English translation of NCT00200486 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying the genetic makeup of head and neck tumors to understand what makes them different from one another and how they might respond to treatment. By analyzing tumor tissue samples from patients undergoing biopsy or surgery, the team hopes to identify specific genetic patterns that could predict a patient's prognosis and guide personalized treatment decisions.
Currently, doctors predict how head and neck cancer will behave using standard clinical information, but this isn't always accurate. By identifying the unique genetic patterns in each tumor, researchers hope to develop better ways to predict outcomes and create new, targeted treatment strategies tailored to each patient's specific cancer.
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If you qualify, researchers will obtain a sample of your tumor tissue during your planned biopsy or surgery, or use previously stored samples if available. Your tissue will be analyzed using genetic and molecular techniques to map its unique characteristics. The study also collects information about your treatment and health outcomes to correlate tumor patterns with how patients respond to therapy. There are no additional visits or treatments required beyond your standard medical care.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Montefiore Medical Center
Collaborators
National Institutes of Health (NIH), National Institute of Dental and Craniofacial Research (NIDCR)
Enrollment target
~1,000 participants
Started
October 2002
Primary completion
December 2030
Last updated on clinicaltrials.gov in April 2026.
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Central contact
Stelby Augustine, RN
Montefiore Medical Center
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