Plain-English translation of NCT00280202 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Lung Cancer research guide →Researchers are trying to understand the genetic changes that cause lung cancer to start and spread by studying tissue samples from patients. This study will look at the DNA in lung cancer cells to find patterns and markers that might help doctors predict how the disease will behave and develop better treatments in the future.
Lung cancer develops when multiple genetic mutations build up in cells over time, but doctors don't yet understand all the key changes that cause this disease or how to predict which patients are at highest risk. This research aims to identify these genetic markers so that future treatments can be more personalized and effective.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will have tissue samples collected either during a biopsy or surgical procedure to remove your lung mass, or researchers may use samples that were already taken. These samples will be sent to the laboratory where scientists will analyze the genetic material to look for patterns and markers associated with lung cancer development and progression. The study does not involve taking any new medications or medications being tested — only the study of tissue you already have or will have removed as part of your regular cancer care.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
University of Pittsburgh
Collaborators
National Institutes of Health (NIH)
Enrollment target
~6,000 participants
Started
June 1996
Primary completion
December 2050
Age range
18 Years and older
Last updated on clinicaltrials.gov in October 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Arjun Pennathur, MD
Professor (with tenure) of Cardiothoracic Surgery
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.