Plain-English translation of NCT00291096 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →This research study is designed for women who have a significantly higher-than-average chance of developing breast cancer. Researchers will collect small tissue samples from the breast, blood samples, and mammogram images to look for biological markers—signs in your cells and blood that might predict cancer risk. By studying these markers over time, researchers hope to better understand who is at highest risk and why.
Many women know they are at higher risk for breast cancer, but doctors don't yet have reliable ways to predict exactly who will develop the disease and when. This study aims to identify the biological signs that best predict cancer development, which could help doctors catch cancer earlier or offer better preventive options in the future.
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You will visit the clinic for a series of appointments where researchers will collect small tissue samples from your breast using a fine needle, take blood samples, and review your mammogram images. You will be asked to share information about your health history and family background. The study will keep in contact with you over time to follow your health and see if any of the markers they measured predict cancer development, making this a long-term commitment but typically involving periodic check-ins rather than frequent visits.
AI-generated summary from trial data · Aug 14, 2026 · Not medical advice
United States
Sponsor
Carol Fabian, MD
Enrollment target
~3,000 participants
Started
August 1989
Primary completion
December 2027
Age range
30 Years – 65 Years
Sex
Female only
Last updated on clinicaltrials.gov in October 2025.
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Central contact
Bruce Kimler, Ph.D.
University of Kansas Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.