Plain-English translation of NCT00515567 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study collects lung tissue samples from patients who are receiving lung transplants. Researchers will compare tissue from healthy lungs with tissue from lungs damaged by pulmonary fibrosis—a disease where lung tissue gradually scars and thickens. By studying these samples, scientists hope to understand how and why this scarring happens so they can develop better treatments in the future.
Pulmonary fibrosis causes permanent lung damage that makes it harder for the body to get oxygen from the air we breathe. Right now, doctors don't fully understand what causes the scarring process. By directly studying lung tissue from affected patients, researchers can unlock new clues about how the disease develops and potentially find ways to stop or slow it down.
You likely qualify if…
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If you qualify, you would donate a sample of your lung tissue during or around the time of your lung transplant surgery. This tissue would then be used by researchers in the laboratory to study the differences between healthy and scarred lung tissue. There are no additional visits or treatments required beyond your transplant procedure.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Enrollment target
~90 participants
Started
February 2006
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2026.
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Central contact
Nickolai Dulin, MD
University of Chicago
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