Plain-English translation of NCT00573027 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study focuses on people who experience chest pain or symptoms of heart disease, but whose large heart arteries show no visible blockages. Researchers want to understand how the small arteries in the heart are working in these patients. The study uses special heart catheterization tests, imaging scans, and blood tests to detect problems in these smaller blood vessels that may be causing symptoms.
Many patients have chest pain and heart disease symptoms even though their large arteries look normal. Doctors believe problems in the small heart arteries may be responsible for these symptoms, but we don't yet understand how common this is, how to diagnose it accurately, or what the long-term outlook is for these patients.
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You will complete medical history questionnaires and then undergo heart catheterization with special testing using medications to assess your small arteries—this adds about 15 minutes to a standard catheterization. You'll also have a non-invasive artery function test called Peripheral Artery Tonometry, possibly a heart MRI scan if recommended, and blood and urine tests. After that, you'll receive follow-up phone calls at 6 weeks, 6 months, and then yearly to check on your health status.
AI-generated summary from trial data · Aug 9, 2026 · Not medical advice
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