Plain-English translation of NCT00575081 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson's Disease research guide →Researchers at Vanderbilt University are building a detailed map of the human brain using information collected from patients who are undergoing stereotactic brain procedures — a type of precise brain surgery used to treat conditions like Parkinson's disease, tremor, epilepsy, and obsessive-compulsive disorder. By gathering brain imaging scans and medical information from many patients before, during, and after their surgery, the team hopes to create a resource that will help doctors plan surgeries more accurately and choose the best treatment locations for devices like deep brain stimulators.
Currently, doctors rely on general knowledge about brain anatomy when planning brain surgery, but every person's brain is slightly different. This study exists to create a population-based map that accounts for these differences, so future doctors can make more personalized and precise decisions about brain surgery — potentially improving outcomes and reducing complications for patients with movement disorders, seizures, and psychiatric conditions.
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If you qualify, the research team will ask your permission to add your brain imaging scans and all medical information related to your brain surgery — including tests done before surgery, observations made during surgery, and your recovery afterward — into a secure, confidential database. You won't need to do anything extra; the team will use information that's already being collected as part of your standard surgical care. All your personal information will be kept private and anonymized in the database.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
United States
Sponsor
Vanderbilt University Medical Center
Collaborators
National Institute for Biomedical Imaging and Bioengineering (NIBIB), National Institute of Neurological Disorders and Stroke (NINDS)
Enrollment target
~5,000 participants
Started
August 2006
Primary completion
August 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
6 Years – 90 Years
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Dario J Englot, MD, Ph.D.
Vanderbilt University, Dept. Neurosurgery
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.