Plain-English translation of NCT00575133 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a long-term observational study that follows patients with non-alcoholic fatty liver disease (a condition where fat builds up in the liver without alcohol being the cause). Researchers will monitor your disease using ultrasound scans, special imaging tests, and blood work collected annually to understand how the disease changes over time. If doctors suspect your disease is getting worse, you may have a liver biopsy (a small tissue sample) taken to confirm the diagnosis.
Fatty liver disease is common but we still don't fully understand how it develops and progresses in different people. This study aims to gather detailed information over many years to help doctors better predict who will get sicker and who will stay stable, which could eventually lead to better treatments.
You likely qualify if…
You likely don't qualify if…
You will have an initial visit where doctors will examine you, take blood samples, and perform ultrasound and special imaging scans of your liver. If needed, a liver biopsy may be done at this time. After that, you'll return for annual visits (once per year) where you'll repeat similar tests—physical exams, blood work, and imaging—so doctors can track how your liver disease is changing. The study will continue for many years, and additional liver biopsies will only be done if your doctor suspects your disease is getting worse.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
Switzerland
Sponsor
University of Zurich
Enrollment target
~150 participants
Started
December 2007
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2012.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Oliver Tschopp
University Hospital Zurich, Endocrinology and Diabetology
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.