Plain-English translation of NCT00762008 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are looking for new blood markers — measurable substances in your blood — that could help doctors predict when compensated heart failure (when symptoms are stable) is about to become decompensated (when symptoms suddenly worsen). Right now, doctors use a marker called BNP, but it doesn't reliably predict when someone's condition will get worse. This study hopes to find better warning signals by studying blood samples from people with heart failure at different stages and healthy people.
Heart failure affects millions of Americans and sends hundreds of thousands to the hospital each year. The challenge is that doctors can't reliably predict when a stable patient will suddenly get much sicker. By identifying new blood markers that signal this dangerous transition, doctors could catch problems earlier and prevent hospitalizations and deaths.
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You would donate blood samples, likely at one or more clinic visits. The researchers will analyze your blood to look for these new warning markers and compare results between people with stable heart failure, those with worsening heart failure, and healthy controls. The study is currently recruiting participants, so the exact number of visits and timing would be discussed with the research team when you enroll.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
UConn Health
Collaborators
CT Department of Public Health
Enrollment target
~500 participants
Started
December 2005
Primary completion
December 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2025.
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Central contact
Fahad E Shah
UConn Health
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.