Plain-English translation of NCT00768820 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This research study is investigating how three genetic conditions—velocardiofacial syndrome, Williams syndrome, and fragile X syndrome—affect thinking, learning, and mental health. Researchers want to understand the specific patterns of psychiatric and cognitive challenges that people with these conditions experience, and how the genetic changes underlying these syndromes connect to these patterns.
Currently, doctors and families don't have enough detailed information about how these three genetic syndromes affect the brain and behavior. By studying a larger group of people with these conditions, researchers hope to better understand what causes these psychiatric and cognitive differences, which could lead to better treatment and support options in the future.
You likely qualify if…
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As a participant, you would undergo psychiatric and cognitive testing as part of this diagnostic study. The research team will examine how your genetic condition relates to thinking patterns, learning abilities, and any psychiatric symptoms you may experience. Visits and specific assessments will be arranged based on your individual needs and the study protocol.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
Israel
Phase
Post-approval monitoring
Sponsor
The Chaim Sheba Medical Center
Enrollment target
~400 participants
Started
May 2001
Primary completion
August 2027
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Doron Gothelf, MD
The Chaim Sheba Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.