Plain-English translation of NCT00991094 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study collects information from cancer patients who are already receiving proton therapy—a type of radiation treatment. Researchers want to understand what short-term and long-term side effects patients experience, and they'll compare this information with the radiation doses patients received. This will help doctors better understand how proton therapy affects healthy tissue and improve treatment planning for future patients.
Proton therapy is a promising cancer treatment, but doctors need more detailed information about its side effects so they can predict and prevent problems in future patients. By collecting data from many patients over time, researchers can identify patterns and create better guidelines for safe treatment.
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You would complete brief questionnaires (15–20 minutes) at the start of treatment, weekly during your radiation therapy, and then every two weeks for three months after treatment ends. You'll also be assessed for side effects weekly during treatment and then 1–3 times within the first 90 days, plus annual follow-up visits. The study uses information you're already collecting during standard cancer care—no extra procedures or medications are involved.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
United States
M.D. Anderson Cancer Center
Enrollment target
~5,000 participants
Started
May 2005
Primary completion
December 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Steven J. Frank
M.D. Anderson Cancer Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.