Plain-English translation of NCT01034033 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →This study is collecting blood samples and tumor tissue from women who carry inherited cancer risk genes (like BRCA1 and BRCA2) or have a strong family history of breast or ovarian cancer. Researchers want to understand how these genetic factors influence cancer risk and how environmental factors may also play a role. By comparing samples from women with and without these genetic risks, scientists hope to better predict who is at highest risk and develop better prevention and treatment strategies.
Many women inherit genes that significantly increase their risk of developing breast or ovarian cancer, but doctors don't fully understand why some carriers develop cancer while others don't, or what other genetic and environmental factors influence this risk. This study aims to fill that knowledge gap by building a detailed database and analyzing genetic patterns that could help personalize cancer prevention and care for high-risk women.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will be asked to donate a blood sample, which researchers will analyze for genetic patterns and risk factors. If you are having surgery for a suspicious pelvic mass, researchers may also request a small sample of tumor tissue for study. You will also be asked to complete a detailed questionnaire about your personal and family medical history, lifestyle, and any environmental exposures. The study is ongoing, so you may be contacted periodically to share updates about your health.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States
Sponsor
Stanford University
Collaborators
Breast Cancer Research Foundation, Susan G. Komen Breast Cancer Foundation
Enrollment target
~3,300 participants
Started
August 2001
Primary completion
January 2099
Age range
18 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in May 2026.
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Central contact
Meredith Mills
Stanford University
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