Plain-English translation of NCT01143454 on ClinicalTrials.gov ↗ ·
This is a discovery study run by the National Heart, Lung, and Blood Institute that welcomes people with rare, unusual, or hard-to-diagnose heart and blood vessel problems. Researchers want to learn more about what causes these conditions, how they develop over time, and whether there are genetic factors that run in families. By studying your medical history and collecting blood or tissue samples, the research team hopes to unlock new insights that could lead to better treatments for you and others with similar conditions.
Many people with rare heart conditions struggle to get answers because so little is known about their disease. This study exists to fill that gap—to gather knowledge about uncommon presentations and genetic factors that contribute to heart disease, so that future patients can be diagnosed faster and treated more effectively.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will likely visit the research clinic where doctors will review your medical history, ask questions about your health, and collect blood or tissue samples. Depending on your condition, you may also be asked to complete questionnaires about your symptoms and health. The study is designed to follow people over time—some participants may have multiple visits—so researchers can track how the disease progresses and learn more about its causes. Samples you donate may be stored and used for future research studies related to heart disease.
AI-generated summary from trial data · Sep 5, 2026 · Not medical advice
United States