Plain-English translation of NCT01258231 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand why some people develop serious complications after heart surgery — like irregular heartbeat, heart attack, kidney problems, or heart failure — while others recover smoothly. This study collects blood and urine samples from 4,000 heart surgery patients to identify genetic factors and protein markers that might predict which patients are at higher risk. By finding these warning signs early, doctors hope to better protect vulnerable patients in the future.
Right now, doctors cannot reliably predict which heart surgery patients will have dangerous complications. If researchers can identify genetic and protein patterns that signal higher risk, doctors could offer extra monitoring or preventive care to the patients who need it most.
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If you enroll, you will provide a blood sample and a urine sample before or around the time of your heart surgery. The research team will follow up after your surgery to track how you recover and watch for any complications. Your genetic information and protein markers will be analyzed to help researchers understand which patients face higher risk.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
United States
Sponsor
Brigham and Women's Hospital
Collaborators
National Heart, Lung, and Blood Institute (NHLBI), Texas Heart Institute
Enrollment target
~4,000 participants
Started
August 2000
Primary completion
August 2030
Age range
20 Years – 90 Years
Last updated on clinicaltrials.gov in August 2024.
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