Plain-English translation of NCT01397669 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how the immune system works differently in people with HIV compared to people without HIV. To do this, they're collecting samples—blood, tissue from the colon, and optional genital secretions—from both groups. These samples will help scientists understand what happens in the body during HIV infection.
Currently, researchers don't fully understand all the ways HIV affects different parts of the immune system throughout the body. By comparing samples from people with and without HIV, scientists can better understand these immune changes and potentially develop better treatments in the future.
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You will have two visits over about 15 days: a screening visit and an enrollment visit. During the enrollment visit at Chulalongkorn University Hospital, you'll undergo a flexible sigmoidoscopy (a procedure where doctors insert a thin camera into your colon to take small tissue samples) and have about 60 milliliters of blood drawn. You may also optionally provide a genital secretion sample. The entire study takes approximately 12 months to complete from start to finish.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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