Plain-English translation of NCT01621594 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Heart imaging using CT scans can help doctors diagnose coronary artery disease, but these scans expose patients to radiation. This study is testing whether newer, lower-dose imaging methods work just as well as standard scans at detecting heart problems and predicting how your heart disease may progress over time.
Current heart imaging scans expose patients to significant radiation, which carries long-term health risks. Researchers want to find ways to get the same clear, accurate pictures of your heart while using much less radiation, and to validate new computer software and artificial intelligence tools that can improve these images.
You likely qualify if…
You likely don't qualify if…
You will come in for a heart imaging scan (a special type of CT scan) that uses new techniques designed to reduce radiation exposure. The scan itself takes only a few minutes. As part of the study, you will also agree to share information about your health over time so researchers can track how well these lower-dose images predicted your heart health outcomes.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
National Heart, Lung, and Blood Institute (NHLBI)
Enrollment target
~5,000 participants
Started
June 2012
Primary completion
April 2027
Age range
18 Years – 100 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Margaret C Lowery, R.N.
National Heart, Lung, and Blood Institute (NHLBI)
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.