Plain-English translation of NCT01631617 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
Researchers are studying how antibiotics like , , and Trimethoprim/Sulfamethoxazole affect the bacteria that naturally live on your skin. This trial will also test whether bleach baths help reduce bacteria in people with moderate-to-severe eczema and signs of bacterial skin infection. The goal is to understand how these treatments change your skin's natural bacteria community over time.
Antibiotics are commonly used to treat eczema flare-ups, especially when bacteria infect the skin, and bleach baths have shown promise in reducing symptoms. However, doctors don't fully understand how these treatments affect the beneficial and harmful bacteria that live on your skin, or whether resistant bacteria can persist for years after treatment stops.
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You will be randomly assigned to receive one of several treatments: an antibiotic by mouth with either placebo or dilute bleach baths, or placebo capsules with either dilute bleach baths or placebo baths. The study involves taking medication for 2 to 8 weeks and possibly taking bleach baths multiple times per week at home. Researchers will collect skin samples at multiple time points to track how the bacteria on your skin change during and after treatment.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States