Plain-English translation of NCT01644903 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers at Northwestern University are studying whether simple blood tests can predict problems after liver transplant surgery. Currently, doctors rely on kidney function tests and tissue biopsies to monitor transplant health, but these methods are slow and sometimes miss early warning signs. This study will collect blood samples from up to 1,000 liver transplant patients to identify genetic markers that could warn of rejection or other complications earlier and more accurately.
After a liver transplant, doctors need better ways to detect rejection and kidney problems before serious damage occurs. Right now, the available tests aren't sensitive or quick enough. By studying blood samples, researchers hope to discover genetic signatures that signal trouble much earlier, giving doctors time to intervene and protect the transplant.
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As a participant, you will donate blood samples at various time points after your liver transplant surgery. The researchers will analyze these samples to look for genetic markers related to transplant rejection and kidney disease. You'll need to be able to comply with the study schedule and follow-up visits, but the main requirement is providing blood samples — a routine and minimally invasive procedure.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
The Scripps Research Institute
Enrollment target
~1,000 participants
Started
April 2010
Primary completion
December 2030
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2026.
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Central contact
Misael Villegas, BA
Northwestern University
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