Plain-English translation of NCT01689584 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a research study that helps doctors understand genetic mutations that can increase the risk of hereditary cancers like breast and ovarian cancer. Researchers are collecting information from families who carry these mutations to learn which ones are truly dangerous and which ones may not increase cancer risk as much as previously thought. By studying how these mutations appear in multiple families, scientists can give patients and their doctors more accurate information about their personal cancer risk.
Many people are found to have genetic mutations, but doctors don't always know for certain whether these mutations actually cause cancer or what level of risk they carry. This study exists to solve that puzzle by gathering evidence from many families, which will help doctors give clearer, more confident answers to patients about their genetic risk and what to do about it.
You likely qualify if…
You likely don't qualify if…
As a participant, you would share your genetic information and family health history with the research team. If you are the main participant (the person in whom the mutation was first found), you'll provide details about your diagnosis and family background. If you're a relative, you may undergo genetic testing or share test results you've already had done as part of your regular medical care. The study is ongoing, and participation involves working with geneticists and cancer specialists to track how the genetic mutation appears across your family.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
France